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1.
Sci Rep ; 8(1): 6879, 2018 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-29720623

RESUMO

This work presents results in the field of advanced substrate solutions in order to achieve high crystalline quality group-III nitrides based heterostructures for high frequency and power devices or for sensor applications. With that objective, Low Temperature Co-fired Ceramics has been used, as a non-crystalline substrate. Structures like these have never been developed before, and for economic reasons will represent a groundbreaking material in these fields of Electronic. In this sense, the report presents the characterization through various techniques of three series of specimens where GaN was deposited on this ceramic composite, using different buffer layers, and a singular metal-organic chemical vapor deposition related technique for low temperature deposition. Other single crystalline ceramic-based templates were also utilized as substrate materials, for comparison purposes.

2.
J Appl Behav Anal ; 9(3): 323-33, 1976.
Artigo em Inglês | MEDLINE | ID: mdl-977518

RESUMO

Reading comprehension, indicated by motor behavior and multiple-choice picture selection called for in written instructions, was taught to an autistic child using verbal prompts, modelling, and physical guidance. The child was rewarded for correct behaviors to training items; nonrewarded probes were used to assess generalization. Probable maintaining events were assessed through their sequential removal in a reversal design. Results showed: (a) following acquisition, performance was maintained at a near-100% level when candy, praise, attention, and training were removed, (b) absence of other persons was correlated with a marked decrease in performance, whereas their presence was associated with performance at near 100%, and (c) performance generalized to probes and across experimenters. Rewards, which may have been reinforcing during acquisition, did not appear necessary to maintain later performance. Instead, presence of others (a setting event) was demonstrated to have control over maintained performance.


Assuntos
Transtorno Autístico/reabilitação , Cognição , Condicionamento Operante , Educação de Pessoa com Deficiência Intelectual , Leitura , Criança , Feminino , Generalização Psicológica , Humanos , Comportamento Imitativo , Reforço Psicológico , Reforço Verbal , Enquadramento Psicológico , Meio Social
3.
Digestion ; 37(2): 79-87, 1987.
Artigo em Inglês | MEDLINE | ID: mdl-2887473

RESUMO

Azodisalicylate (ADS) is one of the possible successors of sulfasalazine in the treatment of ulcerative colitis. The following results were obtained when comparing the influence of ADS on net water and electrolyte transfer in tied-off loops of the rat ileum and colon in vivo with sulfsalazine, 5-aminosalicylic acid, and sulfapyridine. (1) Sulfasalazine, 5-aminosalicylic acid and sulfapyridine had no effect on water and electrolyte transfer of the healthy intestinal mucosa in concentrations up to 400 mg%. (2) ADS showed a concentration-dependent inhibition effect on net water, sodium and chloride absorption and stimulated secretion at concentrations higher than 100 mg%. (3) No morphological alterations of the mucosa could be observed by light and transmission electron microscopy. The observed effect of ADS might have some clinical significance in patients with a decreased absorptive capacity of the colon in ulcerative colitis, in contrast to healthy volunteers, where the high absorptive capacity of the colon might compensate the decreased absorption or stimulated secretion in the small intestine.


Assuntos
Ácidos Aminossalicílicos/farmacologia , Colo/efeitos dos fármacos , Íleo/efeitos dos fármacos , Mucosa Intestinal/efeitos dos fármacos , Ácidos Aminossalicílicos/uso terapêutico , Animais , Colite Ulcerativa/tratamento farmacológico , Absorção Intestinal/efeitos dos fármacos , Mucosa Intestinal/metabolismo , Mesalamina , Ratos , Ratos Endogâmicos , Sulfapiridina/farmacologia , Sulfassalazina/farmacologia
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