Pesquisa | Portal de Pesquisa da BVS

1.

Spatially organized cellular communities form the developing human heart.

Farah, Elie N; Hu, Robert K; Kern, Colin; Zhang, Qingquan; Lu, Ting-Yu; Ma, Qixuan; Tran, Shaina; Zhang, Bo; Carlin, Daniel; Monell, Alexander; Blair, Andrew P; Wang, Zilu; Eschbach, Jacqueline; Li, Bin; Destici, Eugin; Ren, Bing; Evans, Sylvia M; Chen, Shaochen; Zhu, Quan; Chi, Neil C.

Nature ; 627(8005): 854-864, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38480880

2.

Epigenomic analysis of multilineage differentiation of human embryonic stem cells.

Xie, Wei; Schultz, Matthew D; Lister, Ryan; Hou, Zhonggang; Rajagopal, Nisha; Ray, Pradipta; Whitaker, John W; Tian, Shulan; Hawkins, R David; Leung, Danny; Yang, Hongbo; Wang, Tao; Lee, Ah Young; Swanson, Scott A; Zhang, Jiuchun; Zhu, Yun; Kim, Audrey; Nery, Joseph R; Urich, Mark A; Kuan, Samantha; Yen, Chia-an; Klugman, Sarit; Yu, Pengzhi; Suknuntha, Kran; Propson, Nicholas E; Chen, Huaming; Edsall, Lee E; Wagner, Ulrich; Li, Yan; Ye, Zhen; Kulkarni, Ashwinikumar; Xuan, Zhenyu; Chung, Wen-Yu; Chi, Neil C; Antosiewicz-Bourget, Jessica E; Slukvin, Igor; Stewart, Ron; Zhang, Michael Q; Wang, Wei; Thomson, James A; Ecker, Joseph R; Ren, Bing.

Cell ; 153(5): 1134-48, 2013 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-23664764

3.

Coordinating the first heartbeat.

Bloomekatz, Joshua; Chi, Neil C.

Nature ; 622(7981): 37-39, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37759109

4.

Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract.

Sidhwani, Pragya; Leerberg, Dena M; Boezio, Giulia L M; Capasso, Teresa L; Yang, Hongbo; Chi, Neil C; Roman, Beth L; Stainier, Didier Y R; Yelon, Deborah.

Development ; 147(12)2020 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-32439760

5.

Unveiling Complexity and Multipotentiality of Early Heart Fields.

Zhang, Qingquan; Carlin, Daniel; Zhu, Fugui; Cattaneo, Paola; Ideker, Trey; Evans, Sylvia M; Bloomekatz, Joshua; Chi, Neil C.

Circ Res ; 129(4): 474-487, 2021 08 06.

Artigo em Inglês | MEDLINE | ID: mdl-34162224

6.

Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors.

De Val, Sarah; Chi, Neil C; Meadows, Stryder M; Minovitsky, Simon; Anderson, Joshua P; Harris, Ian S; Ehlers, Melissa L; Agarwal, Pooja; Visel, Axel; Xu, Shan-Mei; Pennacchio, Len A; Dubchak, Inna; Krieg, Paul A; Stainier, Didier Y R; Black, Brian L.

Cell ; 135(6): 1053-64, 2008 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-19070576

7.

Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis.

Han, Peidong; Bloomekatz, Joshua; Ren, Jie; Zhang, Ruilin; Grinstein, Jonathan D; Zhao, Long; Burns, C Geoffrey; Burns, Caroline E; Anderson, Ryan M; Chi, Neil C.

Nature ; 534(7609): 700-4, 2016 06 30.

Artigo em Inglês | MEDLINE | ID: mdl-27357797

8.

Integrative analysis of haplotype-resolved epigenomes across human tissues.

Leung, Danny; Jung, Inkyung; Rajagopal, Nisha; Schmitt, Anthony; Selvaraj, Siddarth; Lee, Ah Young; Yen, Chia-An; Lin, Shin; Lin, Yiing; Qiu, Yunjiang; Xie, Wei; Yue, Feng; Hariharan, Manoj; Ray, Pradipta; Kuan, Samantha; Edsall, Lee; Yang, Hongbo; Chi, Neil C; Zhang, Michael Q; Ecker, Joseph R; Ren, Bing.

Nature ; 518(7539): 350-354, 2015 Feb 19.

Artigo em Inglês | MEDLINE | ID: mdl-25693566

9.

FGF signaling enforces cardiac chamber identity in the developing ventricle.

Pradhan, Arjana; Zeng, Xin-Xin I; Sidhwani, Pragya; Marques, Sara R; George, Vanessa; Targoff, Kimara L; Chi, Neil C; Yelon, Deborah.

Development ; 144(7): 1328-1338, 2017 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-28232600

10.

Biallelic Mutations in Citron Kinase Link Mitotic Cytokinesis to Human Primary Microcephaly.

Li, Hongda; Bielas, Stephanie L; Zaki, Maha S; Ismail, Samira; Farfara, Dorit; Um, Kyongmi; Rosti, Rasim O; Scott, Eric C; Tu, Shu; Chi, Neil C; Gabriel, Stacey; Erson-Omay, Emine Z; Ercan-Sencicek, A Gulhan; Yasuno, Katsuhito; Çaglayan, Ahmet Okay; Kaymakçalan, Hande; Ekici, Baris; Bilguvar, Kaya; Gunel, Murat; Gleeson, Joseph G.

Am J Hum Genet ; 99(2): 501-10, 2016 Aug 04.

Artigo em Inglês | MEDLINE | ID: mdl-27453578

11.

Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway.

Hu, Zhilian; Liu, Yang; Huarng, Michael C; Menegatti, Marzia; Reyon, Deepak; Rost, Megan S; Norris, Zachary G; Richter, Catherine E; Stapleton, Alexandra N; Chi, Neil C; Peyvandi, Flora; Joung, J Keith; Shavit, Jordan A.

Blood ; 130(5): 666-676, 2017 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-28576875

12.

Fishing Out the Role of RBPMS2 in Cardiac Splicing.

Holman, Alyssa R; Chi, Neil C.

Circ Res ; 131(12): 1001-1003, 2022 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-36454855

13.

In vivo cardiac reprogramming contributes to zebrafish heart regeneration.

Zhang, Ruilin; Han, Peidong; Yang, Hongbo; Ouyang, Kunfu; Lee, Derek; Lin, Yi-Fan; Ocorr, Karen; Kang, Guson; Chen, Ju; Stainier, Didier Y R; Yelon, Deborah; Chi, Neil C.

Nature ; 498(7455): 497-501, 2013 Jun 27.

Artigo em Inglês | MEDLINE | ID: mdl-23783515

14.

Myocardium and BMP signaling are required for endocardial differentiation.

Palencia-Desai, Sharina; Rost, Megan S; Schumacher, Jennifer A; Ton, Quynh V; Craig, Michael P; Baltrunaite, Kristina; Koenig, Andrew L; Wang, Jinhu; Poss, Kenneth D; Chi, Neil C; Stainier, Didier Y R; Sumanas, Saulius.

Development ; 142(13): 2304-15, 2015 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-26092845

15.

Impaired mitophagy facilitates mitochondrial damage in Danon disease.

Hashem, Sherin I; Murphy, Anne N; Divakaruni, Ajit S; Klos, Matthew L; Nelson, Bradley C; Gault, Emily C; Rowland, Teisha J; Perry, Cynthia N; Gu, Yusu; Dalton, Nancy D; Bradford, William H; Devaney, Eric J; Peterson, Kirk L; Jones, Kenneth L; Taylor, Matthew R G; Chen, Ju; Chi, Neil C; Adler, Eric D.

J Mol Cell Cardiol ; 108: 86-94, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28526246

16.

Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development.

Yang, Hongbo; Fang, Longhou; Zhan, Rui; Hegarty, Jeffrey M; Ren, Jie; Hsiai, Tzung K; Gleeson, Joseph G; Miller, Yury I; Trejo, JoAnn; Chi, Neil C.

Dev Biol ; 404(2): 49-60, 2015 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-26004360

17.

UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development.

Hegarty, Jeffrey M; Yang, Hongbo; Chi, Neil C.

Development ; 140(8): 1713-9, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23533172

18.

Notch signaling regulates venous arterialization during zebrafish fin regeneration.

Kametani, Yoshiko; Chi, Neil C; Stainier, Didier Y R; Takada, Shinji.

Genes Cells ; 20(5): 427-38, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25810153

19.

Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure.

Hashem, Sherin I; Perry, Cynthia N; Bauer, Matthieu; Han, Sangyoon; Clegg, Stacey D; Ouyang, Kunfu; Deacon, Dekker C; Spinharney, Mary; Panopoulos, Athanasia D; Izpisua Belmonte, Juan Carlos; Frazer, Kelly A; Chen, Ju; Gong, Qiuming; Zhou, Zhengfeng; Chi, Neil C; Adler, Eric D.

Stem Cells ; 33(7): 2343-50, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25826782

20.

3-OST-7 regulates BMP-dependent cardiac contraction.

Samson, Shiela C; Ferrer, Tania; Jou, Chuanchau J; Sachse, Frank B; Shankaran, Sunita S; Shaw, Robin M; Chi, Neil C; Tristani-Firouzi, Martin; Yost, H Joseph.

PLoS Biol ; 11(12): e1001727, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24311987

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