RESUMO
Thirty children with cow's milk protein intolerance were submitted to skin tests with either alpha-lactalbumin and casein commercial products or substitutes commonly used for infant feeding. This method showed helpful in choosing the proper milk substitute for affected children.
Assuntos
Caseínas/imunologia , Hipersensibilidade Alimentar/diagnóstico , Lactalbumina/imunologia , Proteínas do Leite/efeitos adversos , Hidrolisados de Proteína/imunologia , Testes Cutâneos , Animais , Criança , Pré-Escolar , Feminino , Hipersensibilidade Alimentar/dietoterapia , Humanos , Lactente , Masculino , Leite/imunologiaRESUMO
RIA dosages of specific IgE antibodies to cow milk, alpha-lactalbumin, beta-lactoglobulin, casein, cheddar and mould cheese were determined in 440 patients. Statistic analysis has been carried out with: 1) the linear regression and correlation coefficient r2: 2) U test of Mann-Whitney and then S test of Kendall Results show that casein has low allergenicity in comparison to other cow's milk proteins. It could be unnecessary to quantify specific IgE to cow milk and cheeses. From the observed data we could suppose that the formulas with casein/blood protein ratio similar to maternal milk may be more allergenic than casein based ones.
Assuntos
Imunoglobulina E/análise , Hipersensibilidade a Leite/imunologia , Proteínas do Leite/imunologia , Adolescente , Adulto , Animais , Caseínas/imunologia , Queijo , Criança , Pré-Escolar , Reações Cruzadas , Feminino , Humanos , Lactente , Lactalbumina/imunologia , Lactoglobulinas/imunologia , Masculino , Teste de Radioalergoadsorção , Estatística como AssuntoRESUMO
R.I.A. dosages of specific IgE antibodies to Dermatophagoides pteronyssinus, Dermatophagoides farinae (house dust mites), Acarus siro, Lepidoglyphus destructor, and Tyrophagus putrescentiae (storage mites) in 467 unselected patients were statistically analyzed. A significant noncorrelation between specific IgE antibodies to storage mites and those to house dust mites has been found, suggesting that storage mites have their own allergenic specificity.