Assuntos
Toxinas Botulínicas/administração & dosagem , Laringectomia/efeitos adversos , Laringoscópios , Laringoscopia/instrumentação , Neurotoxinas/administração & dosagem , Complicações Pós-Operatórias/prevenção & controle , Estudos de Coortes , Humanos , Complicações Pós-Operatórias/etiologia , Espasmo/etiologia , Espasmo/prevenção & controle , Cirurgia Vídeoassistida/instrumentação , Distúrbios da Voz/etiologia , Distúrbios da Voz/prevenção & controleRESUMO
A systematic review and meta-analysis was conducted to evaluate the occult contralateral nodal metastases (OCM) in patients undergoing bilateral neck dissection for surgically treated oropharyngeal squamous cell carcinoma (OPSCC). Following PRISMA guidelines, MEDLINE, Embase and Cochrane Controlled Register of Trials databases were searched for observational and experimental studies until March 2021. Search yielded 175 articles, of which 13 were included. Overall, OCM were seen in 9.8% of patients (95% CI: [5.7, 16.4], 839 patients, 12 studies, I2 65%). For ipsilateral cN0 necks, the OCM rate was 1.7% (95% CI: [0.1, 22.4], 150 patients, 8 studies, I2 0%) and for cN + necks the OCM rate was 9.8% (95% CI: [4.4, 20.3], 429 patients, 8 studies, I2 72%). Occult contralateral nodal metastases are uncommon in OPSCC patients with clinico-radiologically negative ipsilateral necks. Occult rates are higher in the contralateral neck when the ipsilateral neck is clinico-radiologically node positive.
Assuntos
Carcinoma de Células Escamosas , Neoplasias de Cabeça e Pescoço , Humanos , Esvaziamento Cervical , Carcinoma de Células Escamosas de Cabeça e Pescoço/patologia , Estadiamento de Neoplasias , Carcinoma de Células Escamosas/patologia , Estudos Retrospectivos , Metástase Linfática , Neoplasias de Cabeça e Pescoço/patologiaRESUMO
A medical curriculum vitae remains an important document that has 2 main roles: to distinguish candidates applying for various positions, whether that be jobs, posts, grants and it provides a means of keeping an up-to-date record of all your achievements and skills gained thus far. This article provides detailed guidance on how to structure an effective curriculum vitae to maximize your chances of success when applying for these positions.