[Analysis of surgical treatment of 592 cases of cancer of the stomach]. / Analisi dei risultati del trattamento chirurgico di 592 casi di cancro dello stomaco

A series of 592 cases of gastric carcinoma operated on between January 1960 and December 1974 at the S. Croce Hospital at Cuneo is reported. The following observations were made: greater frequency in males (68.25%). The following localizations: cardiac portion 31 cases; fundus 20; body 93 and antropyloric 249. Cancer ulcer in 5.06% of cases. Cancer on the gastric stump in ulcer resections in two cases. The following operations were performed: Gastric resection in 325 cases: operative mortality (O.M.) 5%; 5-year survival: 18%. Total gastrectomy in 38 cases: O.M. 13.1%; 2-year survival: 21%, 5-year survival 5.2%. E.A.G. in 61 cases; O.M. 17.8%; survival: 6 months; maximum 26 months. Gastrostomy in 16 cases; Expl. laparotomy in 150 cases. Survival was only a few months in these two latter groups. Out of all operations 5-year survival was 6.7% and 27.4% in so-called curative interventions. In principle, gastric resection is still considered to be the most valid approach.

[Prognostic significance of cell-mediated immune response in patients with colorectal carcinoma. Preliminary results]. / Significato prognostico della risposta immunitaria cellulo-mediata in pazienti affetti da carcinoma colo-rettale. Risultati preliminari.

Pre-operative skin test response has been evaluated in 50 cases of colorectal carcinoma. Cellular defense's depression was correlated with tumoral staging (p = < 0.001). In B2 and C groups, a higher incidence of metastatic and local recurrences was registered in subjects with low response. These last are suitable for a randomized trial including immunotherapy.

[Diagnostic and therapeutic problems in lesions caused by caustics in the upper digestive tract]. / Problemi diagnostici e terapeutici nelle lesioni da caustici del tratto digestivo superiore.

The Authors report on their experience regarding lesions of the oesophago-gastric tract due to ingestion of caustic substances. Although prognosis of these patients is always severe, the reported data show that it can be improved by a prompt diagnostic and therapeutic approach. Firstly, a correct evaluation of the lesions through endoscopic examination at a very early stage is capable of guiding the search for the most effective therapy, which, in cases of necrotic, coagulative, haemorrhagic or in any way severe lesions, must always be surgical, begun as early as possible and accompanied by broad spectrum antibiotic cover and, above all, total parenteral feeding.

[Idiopathic and torsion-induced omental infarct: case reports and a review of the literature]. / Infarto omentale idiopatico e da torsione: contributo casistico e revisione della letteratura.

The authors review nosologic problems related to the infarction of the greater omentum on the ground of two cases (one idiopathic, the other by torsion) recently observed. Omental infarction, far from being a real diagnostic or surgical problem, is an unusual cause of acute abdomen; resection of the affected omentum is curative in 100% of cases.