[An immunochemical study of the interaction of human trophoblastic beta-glycoprotein with steroid and sex hormones]. / Immunokhimicheskoe izuchenie vzaimodeistviia trofoblasticheskogo beta-glikoproteina cheloveka s steroidnymi i polovymi gormonami.

Human trophoblastic beta-glycoprotein (TBG) was subjected to immunoelectrophoresis with intermediate gel containing hormones. We have observed TBG binding either with cyclopentaneperhydrophenanthrene derivatives (cholesterol, testosterone, progesterone, estradiol, estrone) or their synthetic analogs (sinestrol, diethylstilbestrol). TGB showed markedly higher affinity to estrogens than to other hormones.

[Comparative physico-chemical characteristics of trophoblastic beta-1 glycoprotein preparations isolated from retroplacental blood]. / Sravnitel'naia fiziko-khimicheskaia kharakteristika preparatov trofoblasticheskogo beta1-glikoproteina, vydelennykh iz retroplatsentarnoi krovi.

Trophoblastic beta 1-glycoprotein preparations (TBG-1, TBG-2) isolated by different methods preserve their physicochemical and immunochemical properties. According to the data of disk-electrophoresis and densitometry TBG-1 preparation obtained using two-stage method is highly purified and protein yield is about 20%, while TBG-2 isolated by multi-stage method has a small number of admixture proteins.