RESUMO
This study examined whether cognitive control mediated the association between socioeconomic status (SES; composite of income-to-needs ratio and parent education) and changes in risk-taking behaviors. The sample included 167 dyads of adolescents (53% male; Mage = 14.07 years at Time 1) and their parents, assessed annually across 4 years. Parents reported socioeconomic variables at Time 1. Adolescents reported risk-taking behaviors at Times 1 and 4, and completed a functional magnetic resonance imaging cognitive control task at Times 2 and 3. Lower SES was associated with lower behavioral (but not neural) cognitive control, which was associated with increases in risk-taking behaviors. The findings suggest that elevated socioeconomic risk may compromise cognitive control which can cascade into maladaptive behaviors in adolescence.
Assuntos
Pais , Classe Social , Adolescente , Cognição , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Assunção de RiscosAssuntos
Antineoplásicos , Tamponamento Cardíaco , Piridazinas , Antineoplásicos/efeitos adversos , Tamponamento Cardíaco/induzido quimicamente , Tamponamento Cardíaco/diagnóstico , Humanos , Imidazóis/efeitos adversos , Inibidores de Proteínas Quinases/efeitos adversos , Piridazinas/efeitos adversosRESUMO
Interluekin-9 (IL-9) is produced predominantly by helper T cells such as Th2 and Th9 cells. It normally functions through the activation of a JAK/STAT pathway and plays a critical role in immunity and the pathogenesis of cancer. In cancer, it yields different responses depending on the cancer cell line involved. This review is a summary of what is known about the involvement of IL-9 in various cancer cell lines as well as its role in immunity with a focus on allergic responses.