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1.
AJNR Am J Neuroradiol ; 15(10): 1871-83, 1994 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-7863937

RESUMO

PURPOSE: To report the anatomic and radiologic development of the transverse, sigmoid, and occipital sinuses, the emissary veins, and the jugular bulb formation from the jugular sinus in humans before and after birth. METHODS: Roentgenograms of 33 injected brains showing the cranial venous system in human fetuses from 3 to 7 months of gestational age and cerebral angiograms of newborns and infants up to 6 years of age (23 clinical cases) were made and analyzed in detail. Special attention was focused on the inner diameters of the transverse and sigmoid sinuses and of the internal jugular veins, particularly at the sigmoid sinus-internal jugular vein junction. RESULTS: Marked increase in venous flow from the rapidly growing cerebral hemispheres leads to ballooning of the transverse sinuses in the absence of an increase in the inner diameters of the sigmoid and jugular sinuses. The ballooning also results in formation of the occipital sinus, marginal sinus around the foramen magnum, and emissary veins. The formation of the jugular bulbs from the jugular sinuses begins after birth when a shift from a fetal to a postnatal type of circulation (or from a lying-down position to an erect posture) takes place. CONCLUSION: The morphological changes of the posterior fossa dural sinuses, emissary veins, and jugular bulb are closely related to the development of the brain, shift to postnatal type of circulation, and postural hemodynamic changes.


Assuntos
Veias Cerebrais/embriologia , Cavidades Cranianas/embriologia , Veias Jugulares/embriologia , Angiografia Cerebral , Veias Cerebrais/patologia , Criança , Pré-Escolar , Fossa Craniana Posterior/embriologia , Fossa Craniana Posterior/patologia , Cavidades Cranianas/patologia , Feminino , Idade Gestacional , Humanos , Lactente , Recém-Nascido , Veias Jugulares/patologia , Masculino , Gravidez , Valores de Referência
2.
Neurosurgery ; 25(2): 281-6, 1989 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2671785

RESUMO

We report the cases of two patients, each of whom had two separate angiographically demonstrable intracerebral arteriovenous malformations (AVMs). One patient had an intraventricular hemorrhage with AVMs in the basal ganglia and the insula on the left side, and the other had a pontine hemorrhage with AVMs in the pons and the occipital lobe on the right side. The AVMs in the former patient were removed totally without residual neurological deficit. We discuss the diagnostic problems of multiple intracerebral AVMs and stress the need for thorough neuroradiological evaluation so as not to miss an occult AVM. We also stress the necessity of total excision of all the lesions and point out several problems faced in surgery for AVMs.


Assuntos
Malformações Arteriovenosas Intracranianas/diagnóstico por imagem , Adulto , Angiografia Cerebral , Feminino , Humanos , Malformações Arteriovenosas Intracranianas/patologia , Malformações Arteriovenosas Intracranianas/cirurgia , Masculino , Tomografia Computadorizada por Raios X
3.
Neurosurgery ; 38(4): 671-7; discussion 677, 1996 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-8692383

RESUMO

We report seven patients with scalp arteriovenous malformations, including two patients with lesions > 10 cm in diameter, who were successfully treated. The principal complaint of each patient was a deforming mass. Each of four patients had a history of blunt traumatic injury. The lesions, each consisting of the nidus, feeders, and draining veins, evolved in all patients. The nidus consisted of fistulae, which exhibited various angioarchitectures as revealed by angiography. A hemangiomatous component was histologically recognized in one patient. In five patients, in whom the lesions were relatively small and whose nidi included only large fistulae, the malformations were remedied by surgical intervention alone or were cured with embolization alone using liquid adhesives. In the two patients with lesions > 10 cm, the nidi consisted of numerous large fistulae and plexiform fistulae in one patient and plexiform fistulae and a hemangiomatous component in the other patient. These patients were treated with a combination of transarterial embolization and surgical intervention. Preoperative embolization greatly reduced blood loss during resection. Total excision and scalp reconstruction using a soft tissue expander were performed in both patients. The cosmetic results were excellent in all of the patients, and no recurrence has been recognized during the follow-up period, which ranges from 31 to 99 months. The treatment of scalp arteriovenous malformations should strive to improve deforming features and to attain a permanent cure. Because each nidus includes a variety of anomalous angioarchitectural features, there should be different means and a combination of treatments for each patient. Embolization alone could be adequate treatment in relatively small lesions, the nidi of which consist only of several large fistulae. For malformations with more extensive, large fistulae or with anomalous components other than large fistulae, a combined endovascular and surgical approach and scalp reconstruction seems to be the best treatment.


Assuntos
Malformações Arteriovenosas/cirurgia , Couro Cabeludo/irrigação sanguínea , Adulto , Angiografia , Malformações Arteriovenosas/patologia , Terapia Combinada , Embolização Terapêutica , Feminino , Hemangioma/patologia , Hemangioma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia , Dispositivos para Expansão de Tecidos
4.
Mt Sinai J Med ; 64(3): 197-206, 1997 May.
Artigo em Inglês | MEDLINE | ID: mdl-9145670

RESUMO

The parenchymal veins, especially the deep medullary veins, of the cerebral hemispheres were studied in detail by analyzing the stereoroentgenograms of multiple brain slices of postmortem injected brain specimens (injected into the internal carotid arteries in 17 cases and into the jugular veins in 12 cases). The presence of four zones--the first (or outer), the second (or candelabra), the third (or palmate) and the fourth (or subependymal) zone--of venous convergence was confirmed within the centrum semiovale, particularly in the frontoparietal area. Other venous convergences such as those related to the optic radiation in the para-atrial area were also found. Arterial branching zones were also observed in the areas similar to those of the medullary veins. It appears that these converging zones are created by rapidly growing crossing nerve fiber tracts, i.e., projection, commissural, and association fibers which grow rapidly during intrauterine and postnatal life. Pathogenesis of medullary venous malformation is also discussed from anatomical viewpoint, venoarchitecture of the pial, parenchymal, and subependymal veins and of the dural venous sinuses. The possibility of a similar mechanism (partial, mild, repetitive venoocclusive disease developing over a long period with fluctuating venous pressure) leading to formation of most (if not all) cases of medullary venous malformation and in some, if not many, cases of cerebral vascular malformations [aside from gene abnormality (chromosome 7) in familial cavernous angiomatosis, particularly in Hispanic American or other familial hereditary conditions] has been postulated.


Assuntos
Córtex Cerebral/irrigação sanguínea , Veias Cerebrais/anatomia & histologia , Malformações Arteriovenosas Intracranianas/patologia , Humanos , Malformações Arteriovenosas Intracranianas/diagnóstico por imagem , Radiografia
5.
Clin Neuropathol ; 5(2): 47-52, 1986.
Artigo em Inglês | MEDLINE | ID: mdl-3708952

RESUMO

Brain anomalies in 9 cases of cytogenetically proven 18 trisomy were reported. In addition to the various cerebral anomalies such as gyral or lobar abnormalities, hippocampal dysplasia, abnormal lateral geniculate body, agenesis or hypoplasia of the corpus callosum, absent or hypoplastic olfactory nerves, small optic tracts, and dysplasia of the inferior olivary nucleus, hypoplasia of the cerebellum and ventral pons was found in all cases. Cranial computed tomography was performed and revealed cerebellar and pontine hypoplasia with or without hypoplasia of the posterior cranial fossa as a characteristic finding in all 9 cases. A comparative morphometric study was done using age-matched controls. Macroscopically, the weight ratio of the cerebellum and brain stem to the whole brain was reduced compared with the controls. Microscopically, the thickness of the internal granular layer of the cerebellum was reduced especially at the convex area.


Assuntos
Encéfalo/anormalidades , Cromossomos Humanos 16-18 , Trissomia , Encéfalo/diagnóstico por imagem , Tronco Encefálico/anormalidades , Tronco Encefálico/patologia , Cerebelo/anormalidades , Cerebelo/patologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Tamanho do Órgão , Tomografia Computadorizada por Raios X
6.
Surg Neurol ; 40(3): 230-5, 1993 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-8346477

RESUMO

The authors report the case of a 43-year-old woman with a venous malformation of the mesencephalon occluding the sylvian aqueduct. Neuroradiological investigations suggested aqueductal stenosis, while the presence of a venous malformation was diagnosed by both magnetic resonance imaging and an angiogram, and was visualized using a neuroendoscope. This is the first reported instance of a venous malformation being observed in situ and the subependymal course taken.


Assuntos
Aqueduto do Mesencéfalo/patologia , Malformações Arteriovenosas Intracranianas/complicações , Mesencéfalo/irrigação sanguínea , Adulto , Constrição Patológica/etiologia , Feminino , Humanos
7.
Neurol Med Chir (Tokyo) ; 31(9): 582-5, 1991 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-1723172

RESUMO

Four rare cases of aneurysm of the lenticulostriate artery (LSA) are presented. LSA aneurysms were located at the origin in three patients and distally in one. Two cases were of multiple aneurysms, one was associated with hypertensive intracerebral hematoma (putaminal hemorrhage), and the other with moyamoya disease. Two patients were successfully treated by microsurgical procedures. The occurrence of LSA aneurysm suggests that aneurysm formation and growth are accentuated by hemodynamic alteration and stress.


Assuntos
Aneurisma Intracraniano , Adulto , Angiografia Cerebral , Hemorragia Cerebral/complicações , Feminino , Hematoma/complicações , Humanos , Aneurisma Intracraniano/diagnóstico por imagem , Aneurisma Intracraniano/etiologia , Aneurisma Intracraniano/cirurgia , Pressão Intracraniana , Masculino , Pessoa de Meia-Idade , Doença de Moyamoya/complicações , Ruptura Espontânea
8.
Neurol Med Chir (Tokyo) ; 29(9): 857-60, 1989 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-2480549

RESUMO

We report the rare of occurrence of a medullary venous malformation (MVM) with an arterial component associated with a saccular aneurysm on the opposite side. This 49-year-old male patient was admitted with headache and vomiting. He was diagnosed as having a subarachnoid hemorrhage on the basis of bloody cerebrospinal fluid. Angiography revealed a saccular aneurysm at the junction of the internal carotid and posterior communicating arteries on the left side. A MVM with an arterial component was also seen in the right basal frontal lobe. On the seventh hospital day, the aneurysm was clipped via a left frontotemporal craniotomy. The postoperative course was uneventful. There are many hypotheses concerning cerebral aneurysms; some are thought to derive from persistent primitive arteries in the early fetal period. On the other hand, MVM is thought to be intimately related to arteriovenous malformation, which is believed to develop from the premordial vascular plexus, also in early fetal life.


Assuntos
Neoplasias Encefálicas/complicações , Hemangioma/complicações , Aneurisma Intracraniano/complicações , Hemorragia Subaracnóidea/etiologia , Neoplasias Encefálicas/diagnóstico , Neoplasias Encefálicas/diagnóstico por imagem , Hemangioma/diagnóstico , Hemangioma/diagnóstico por imagem , Humanos , Aneurisma Intracraniano/cirurgia , Masculino , Pessoa de Meia-Idade , Radiografia , Ruptura Espontânea , Hemorragia Subaracnóidea/cirurgia
9.
Neurol Med Chir (Tokyo) ; 33(10): 706-9, 1993 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-7505900

RESUMO

A 56-year-old male presented with a posterior fossa cavernous angioma manifesting as persistent headache with mild neck stiffness. Lumbar puncture revealed subarachnoid hemorrhage (SAH). Repeated four-vessel angiography failed to identify the source of the SAH. Magnetic resonance (MR) imaging demonstrated multiple small lesions in the posterior fossa and cerebral hemispheres, and the SAH. A mass arising from the biventral lobule of the right cerebellar hemisphere extended exophytically into the cisterna magna with intratumoral hemorrhage. These findings were compatible with the presumptive diagnosis of SAH from the mass at the right biventral lobule. The lesion was totally removed through a suboccipital craniectomy without sequelae. The histological diagnosis was cavernous angioma. Intracranial cavernous angioma presenting only as SAH has never been reported before. The use of MR imaging in establishing the diagnosis of vascular malformations is emphasized, particularly when neither computed tomography nor angiography can adequately visualize the origin of SAH.


Assuntos
Neoplasias Cerebelares/complicações , Hemangioma Cavernoso/complicações , Hemorragia Subaracnóidea/etiologia , Neoplasias Cerebelares/diagnóstico , Hemangioma Cavernoso/diagnóstico , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade
10.
No Shinkei Geka ; 7(10): 945-51, 1979 Oct.
Artigo em Japonês | MEDLINE | ID: mdl-522952

RESUMO

Not infrequently, it is difficult to differentiate the chiasmal meningioma from other suprasellar tumors, especially pituitary adenoma and craniopharyngioma. Authors examined 7 cases of chiasmal meningioma from neurological, endocrinological and neuroradiological points of view in comparison with the cases of pituitary adenoma and craniopharyngioma. As the results, the following features can be regarded as the differential characteristics of the chiasmal meningioma. 1) It was predominated in female of over 40 years of age. 2) Duration of the symptoms before admission was usually 2--3 years. 3) Disturbance of visual acuity and defect of visual field were initially unilateral in most of the cases, then extended to the other side when the disturbance of one eye had become severe. Visual field defect tended to be of irregular bitemporal hemianopsia with frequent involvement of peripheral nasal field. 4) Evidence of the endocrine disturbance were very scanty until the end stage. 5) Postero-superior elevation of A1 portion of the anterior cerebral artery in the tuberculum sellae meningioma was one of the pathognomonic features. 6) In the case of meningioma extending from tuberculum sellae to dorsum sellae or originated from dorsum sellae, PEG showed a finding of "capping on the dorsum sellae" and the tumor shadow over the posterior clinoid process took different feature from pituitary adenoma or craniopharyngioma.


Assuntos
Neoplasias Meníngeas/diagnóstico , Meningioma/diagnóstico , Quiasma Óptico , Adenoma/diagnóstico , Adolescente , Adulto , Idoso , Craniofaringioma/diagnóstico , Diagnóstico Diferencial , Feminino , Humanos , Neoplasias Meníngeas/diagnóstico por imagem , Meningioma/diagnóstico por imagem , Pessoa de Meia-Idade , Neoplasias Hipofisárias/diagnóstico , Radiografia
11.
No Shinkei Geka ; 14(3 Suppl): 411-6, 1986 Mar.
Artigo em Japonês | MEDLINE | ID: mdl-3703143

RESUMO

UNLABELLED: A rare case of cerebellar astrocytoma presenting with cerebellar hemorrhage is reported. On reviewing the literature, we could collect only four other cases of spontaneous hemorrhage in cerebellar astrocytomas. CASE: On April 5, 1984, a 15-year-old boy noted a sudden onset of headache, vomiting and vertigo and became lethargic and confused. He was admitted on the next day. General examinations, including bloodpressure, temperature and laboratory tests, were found to be normal upon admission. The patient was in somnolence with nystagmus and left dysdiadochokinesis. The result of the left nose to finger test was poor. Computerized tomography revealed a mass leison with calcification and hemorrhage in the paramedian part of the cerebellum. Fourty days after admission, suboccipital osteoplastic craniotomy was performed. A hematoma was found in the paramedian part of the cerebellum. A tumor mass with rich vascularity was completely removed together with the hematoma. Histologically this tissue was a low grade fibrillary astrocytoma accompanying calcification and hemosiderin suggesting tumoral hemorrhage. He regained his neurological functions satisfactorily and was discharged 2 months later.


Assuntos
Astrocitoma/complicações , Doenças Cerebelares/etiologia , Neoplasias Cerebelares/complicações , Hemorragia Cerebral/etiologia , Adolescente , Astrocitoma/diagnóstico por imagem , Astrocitoma/patologia , Encéfalo/diagnóstico por imagem , Neoplasias Cerebelares/diagnóstico por imagem , Neoplasias Cerebelares/patologia , Diagnóstico Diferencial , Humanos , Masculino , Ruptura Espontânea , Tomografia Computadorizada por Raios X
12.
No Shinkei Geka ; 14(8): 1045-9, 1986 Jul.
Artigo em Japonês | MEDLINE | ID: mdl-3748298

RESUMO

Intracranial hemorrhage in neonatal infants is mostly noted in the subependymal or subdural space. The former is characteristically noted in premature infants and is attributed to hemorrhage from the subependymal germinal matrix layer. The latter is prevalently noted in full-term neonatal infants and is thought to be associated with injury in the vicinity of the falx cerebri or tentorium cerebelli. We report two cases of intracerebral hemorrhage, which is relatively rare in full-term neonatal infants. In both of them hematoma was located in the left frontal area adjacent to the coronal suture. Angiogram did not reveal any causative abnormality. From CT scan and intraoperative findings it is speculated that the hemorrhage was caused by moulding at the coronal suture. In other words, moulding made the frontal bone slipped in beneath the parietal bone at the coronal suture causing pressure over the brain. The hemorrhage is thought to be caused by contusion of fragile vasculature of neonatal infants.


Assuntos
Hemorragia Cerebral/etiologia , Angiografia Cerebral , Artérias Cerebrais/lesões , Hemorragia Cerebral/diagnóstico por imagem , Contusões/complicações , Feminino , Osso Frontal/anatomia & histologia , Humanos , Recém-Nascido , Osso Parietal/anatomia & histologia
13.
No Shinkei Geka ; 14(7): 857-63, 1986 Jun.
Artigo em Japonês | MEDLINE | ID: mdl-3762854

RESUMO

A seven-year-old boy who was admitted for surgical treatment for intractable epilepsy was found to have a ganglioglioma in his left parietal lobe. Since four years old, he had been suffering from the seizure and treated with various anticonvulsants without satisfactory effects. As its frequency increased, the dose had to be increased. Thus, it was sought for the possible surgical approach. On the CT scans, an egg size low density zone without contrast enhancement was observed in the subcortical region of his parietal lobe. There was marked thinning on inner table of the skull immediately above the zone. He was operated under fronto-temporo-parietal craniotomy. When the dura matter was opened, pale cerebral cortex protruded. Complete removal of the tumor was not possible, since there was not clear boundary between the mass and normal tissue. Based on histological study, it was diagnosed as ganglioglioma, because its main body contained increased number of glia which had deeply stained ununiform size nuclei. After the operation, he showed neither motor paralysis nor sensory disturbance and was able to sustain his activity with less amount of anticonvulsant.


Assuntos
Neoplasias Encefálicas/patologia , Neuroblastoma/patologia , Lobo Parietal , Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/cirurgia , Criança , Humanos , Masculino , Neuroblastoma/diagnóstico por imagem , Neuroblastoma/cirurgia , Radiografia , Convulsões/etiologia
14.
No Shinkei Geka ; 14(9): 1105-10, 1986 Aug.
Artigo em Japonês | MEDLINE | ID: mdl-3774099

RESUMO

In order to show the vascular anatomy in periventricular region, two adult cases of moyamoya disease with intracerebral hemorrhage extending into lateral ventricle were presented. And we discussed the relation between the vascular anatomy and the form of hemorrhage in moyamoya disease. The first case was a 46-year-old woman admitted for nausea and vomiting following headache for four days. CT scan revealed a high density area in the upper portion of body of right lateral ventricle showing intracerebral hemorrhage which extended into the lateral ventricle. On angiogram, typical moyamoya disease was noted. The ventriculofugal arteries from the posterior lateral choroidal artery was detected which indicated developed ventriculofugal perfusion. The second case was a 52-year-old man who was hospitalized sudden onset of headache, vomiting and consciousness disturbance. CT scan revealed a high density area suggesting of hemorrhage in the head of right caudate nucleus. It perforated into the right anterior horn of lateral ventricle with spreading over the other ventricles. We observed similar findings on the angiograms to the first case. In this case, however, the lateral striate arteries were involved instead of the posterior lateral choroidal artery. It should be pointed out that, in both cases, the area of hemorrhage in CT scan coincided with the area of developed ventriculofugal perfusion in angiograms.


Assuntos
Arteriopatias Oclusivas/etiologia , Hemorragia Cerebral/diagnóstico por imagem , Ventrículos Cerebrais/irrigação sanguínea , Doença de Moyamoya/etiologia , Angiografia Cerebral , Hemorragia Cerebral/complicações , Circulação Colateral , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doença de Moyamoya/diagnóstico por imagem
15.
No Shinkei Geka ; 20(4): 439-44, 1992 Apr.
Artigo em Japonês | MEDLINE | ID: mdl-1570068

RESUMO

The clinical and pathological aspects of two large arteriovenous malformations which were removed totally after preoperative embolization using ethylene vinyl alcohol copolymer (EVAL) were studied. The material, which is not adhesive, is handled easily during the procedure of embolization. However, it involves some risks because it might migrate to and occlude the normal branches of the brain and pass through the nidus to the venous system. Histopathological study of AVM nidus which was removed showed embolic materials within the vessels and inflammatory reaction of the vessel wall and its surrounding tissue. There were patchy hemorrhages within the AVM nidus and its surrounding brain tissue. Recanalization was also found within the occluded vessels. These findings suggest that preoperative embolization has some risk of causing intracerebral hemorrhage after the embolization. AVM should be removed surgically as a radical treatment if the patient is able to tolerate the operation.


Assuntos
Embolização Terapêutica , Malformações Arteriovenosas Intracranianas/terapia , Polivinil/uso terapêutico , Adolescente , Adulto , Hemorragia Cerebral/etiologia , Terapia Combinada , Embolização Terapêutica/efeitos adversos , Humanos , Malformações Arteriovenosas Intracranianas/patologia , Malformações Arteriovenosas Intracranianas/cirurgia , Masculino , Cuidados Pré-Operatórios
16.
No Shinkei Geka ; 19(6): 517-24, 1991 Jun.
Artigo em Japonês | MEDLINE | ID: mdl-1881520

RESUMO

We report the clinical features, radiological studies, operative procedures and results, and follow-up data in 29 patients with meningiomas of the tentorium and its surrounding structures. The cases represented 22.5% of all the intracranial meningiomas operated on in a 15 year period and were divided into three groups, depending on their main attachments, tentorial, cerebellopontine angle (dorsal aspect of the petrous ridge) and others. Tumor size was generally large and 13 cases were larger than 5 cm. The most common tumor site was along or near the superior petrosal sinus and transverse-sigmoid junction in cases involving the tentorium, and medial to the porus acousticus in cases involving the cerebellopontine angle. Different operative approaches to these tumors were carried out, depending on their location. The tumors in the lateral or medial petrous ridge were approached mainly with a suboccipital craniectomy using a retromastoid incision. Total removal was carried out in 80% of the tentorial cases, in 46.2% of cerebellopontine angle cases, and in the 83.3% in the others. Total operative mortality rate was zero. Follow-up periods ranged up to 5 years 5 months in the tentorial cases, 4 years 6 months in cerebellopontine angle cases, and 7 years 1 month in the others. Long-term results were good in 21 cases (72.4%), fair in 3 cases (10.3%) and poor in 2 (6.9%). Three patients died due to tumor recurrence. One of them suffered lung metastasis, and two of them suffered extensive local recurrences. We recommend the retromastoid approach combined with the petrosal approach, if the CPA tumor is large enough and extends to the retroclival region.


Assuntos
Meningioma/patologia , Neoplasias Supratentoriais/patologia , Adulto , Idoso , Neoplasias Cerebelares/patologia , Neoplasias Cerebelares/cirurgia , Ângulo Cerebelopontino , Feminino , Seguimentos , Humanos , Masculino , Meningioma/cirurgia , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/patologia , Recidiva Local de Neoplasia/cirurgia , Prognóstico , Reoperação , Neoplasias Supratentoriais/cirurgia
17.
No To Shinkei ; 36(6): 601-7, 1984 Jun.
Artigo em Japonês | MEDLINE | ID: mdl-6466509

RESUMO

The pathophysiology of cerebral tumor mass in cases of systemic non-Hodgkin's lymphoma is not well known. We experienced with two cases with this lesion. The purpose of this report is not only case presentation but also an analysis of cases from the literature from the clinical, radiological, histological, immunological and therapeutic aspects. Case 1 was a 82-year-old man who had weakness in the right arm and for the past month. For about two years he had been received anticancer chemotherapy because of a systemic malignant lymphoma at another hospital. Neurological examination revealed disorientation and right hemiparesis. Microscopic and immunological studies of the biopsy specimen of the enlarged supraclavicular node showed a non-Hodgkin's B-cell lymphoma of the diffuse large cell type according to the Lymphoma Study Group (LSG) classification. The clinical stage (CS) of the lymphoma was IV except for the CNS lesion by systemic examination including lymphography. CT scan on admission revealed remarkable enhancement of a nodular high density area near the lateral ventricle, accompanied by surrounding low density. Angiography failed to reveal a tumor stain. CSF cytology was positive although no pleocytosis was observed. Case 2 was a 70-year-old man who had weakness of the right foot for two weeks. About three years ago he underwent orchiectomy for a testicular tumor at another hospital. Neurological examination revealed disorientation, memory loss and right hemiparesis.(ABSTRACT TRUNCATED AT 250 WORDS)


Assuntos
Neoplasias Encefálicas/patologia , Linfoma/patologia , Idoso , Encéfalo/diagnóstico por imagem , Neoplasias Encefálicas/líquido cefalorraquidiano , Neoplasias Encefálicas/diagnóstico por imagem , Angiografia Cerebral , Humanos , Linfoma/líquido cefalorraquidiano , Linfoma/diagnóstico por imagem , Masculino , Invasividade Neoplásica , Tomografia Computadorizada por Raios X
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