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1.
J Clin Med ; 12(22)2023 Nov 17.
Artigo em Inglês | MEDLINE | ID: mdl-38002756

RESUMO

Dual antiplatelet therapy (DAPT), comprising aspirin and a P2Y12 receptor inhibitor, is the cornerstone of post-percutaneous coronary intervention treatment to prevent stent thrombosis and reduce the risk of adverse cardiovascular events. The selection of an optimal DAPT regimen, considering the interplay of various antiplatelet agents, patient profiles, and procedural characteristics, remains an evolving challenge. Traditionally, a standard duration of 12 months has been recommended for DAPT in most patients. While contemporary guidelines provide general frameworks, DAPT modulation with longer or shorter treatment courses followed by aspirin or P2Y12 inhibitor monotherapy are evolving towards an individualized strategy to optimize the balance between efficacy and safety. This review comprehensively examines the current landscape of DAPT strategies after coronary stenting, with a focus on emerging evidence for treatment individualization.

2.
J Sports Sci Med ; 11(3): 557-61, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-24149368

RESUMO

One of the diagnostic criteria in order to differentiate between physiological and pathological left ventricular hypertrophy is the wall thickness reduction after at least 3-month detraining period, which is considered a marker of the athlete's heart. This report describes detraining-related regression of LV hypertrophy and improvement in myocardial deformation in a junior athlete likely to have hypertrophic cardiomyopathy. Key pointsHypertrophic cardiomyopathy in adolescent athletes can be discovered by 12-lead ECGPhysical training is an important trigger for the clinical presentation of hypertrophic cardiomyopathyReverse LV remodeling (wall thickness reduction) with detraining is a common echocardiographic finding in athletes with physiological hypertrophyThis report demonstrates that reverse remodeling can also be found in adolescent athletes likely to have hypertrophic cardiomyopathy.

3.
Int J Cardiol ; 137(3): e51-3, 2009 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-19411118

RESUMO

Hypertrophic cardiomyopathy (HCM) is one of the commonest causes of sudden cardiac death in young athletes. Over the last years, the Italian preparticipation screening programme strongly contributed to discriminate athletes showing borderline (grey-area) left ventricular hypertrophy or fulfilling precise diagnostic criteria for HCM, thanks to the framework of testing performed yearly before competitions. We present the case of a junior athlete in whom dramatic ECG changes suggestive for HCM became manifest during the last year training activity.


Assuntos
Cardiomiopatia Hipertrófica/fisiopatologia , Eletrocardiografia , Adolescente , Cardiomiopatia Hipertrófica/diagnóstico , Ecocardiografia , Humanos , Itália , Masculino , Programas de Rastreamento/normas , Futebol/fisiologia
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