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1.
J Shoulder Elbow Surg ; 32(2): 318-325, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36049701

RESUMO

BACKGROUND: Restoration of the native glenohumeral anatomy is an important consideration in obtaining optimal range of motion (ROM) after anatomic total shoulder arthroplasty (TSA). Recently, a new stemless TSA system has been developed that uses both a multiplanar osteotomy (MPO), to improve the surgeon's ability to restore humeral center of rotation (COR), and an elliptical humeral head to improve ROM. The purpose of our study was to compare the difference in early postoperative ROM and restoration of radiographic COR, between this stemless TSA and standard stemmed TSAs. METHODS: This was a retrospective review of 50 consecutive primary TSAs performed by a single surgeon for glenohumeral osteoarthritis. The initial cohort underwent TSA with a standard stemmed humeral component with a circular humeral head (n = 25), whereas the subsequent cohort underwent stemless TSA using an MPO and an elliptical humeral head (n = 25). Postoperative data collection included active shoulder ROM as measured by goniometer, complications or revision surgery, and measurements of radiographic COR. Patients were assessed at 6 weeks, 12 weeks, 6 months, and 12 months after surgery. Change in COR was determined on postoperative radiographs by 2 fellowship-trained surgeons on 2 separate occasions. Intra- and interrater reliability were computed using intraclass correlation coefficients. RESULTS: For both mean forward flexion (FF) and external rotation (ER), there was greater ROM in the MPO-elliptical group at all time points, which was statistically significant. Mean change in FF favored the MPO group at 6 and 12 weeks and was statistically significant and above the minimal clinically important difference (MCID): 6 weeks, standard -15.8° vs. MPO 8.4° (P = .004); 12 weeks, standard 6.4° vs. MPO 29.2° (P = .001). Mean change in ER favored the MPO group at 6 weeks and was statistically significant: standard 5.4° vs. MPO 14.0° (P = .02). There were no revision surgeries in either group. Average change in COR was 2.7 mm in the standard group and 1.8 mm in the MPO-elliptical group, which was statistically significant (P < .001). Number of patients with >3 mm of difference in COR was 10 (40%) in the standard group and 1 (5%) in the MPO-elliptical group, which was statistically significant (P = .002). Average intraclass correlation coefficient was 0.75, indicating good reliability within and between surgeon measurements. CONCLUSION: The use of a multiplanar osteotomy and elliptical humeral head was associated with improved early range of motion and better reproduction of the radiographic COR compared with standard stemmed TSA.


Assuntos
Artroplastia do Ombro , Articulação do Ombro , Humanos , Artroplastia do Ombro/métodos , Articulação do Ombro/diagnóstico por imagem , Articulação do Ombro/cirurgia , Cabeça do Úmero/diagnóstico por imagem , Cabeça do Úmero/cirurgia , Reprodutibilidade dos Testes , Amplitude de Movimento Articular , Estudos Retrospectivos , Resultado do Tratamento
2.
J Shoulder Elbow Surg ; 32(9): 1893-1900, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37075936

RESUMO

BACKGROUND: Reverse total shoulder arthroplasty (RTSA), initially indicated for cuff tear arthropathy, is increasingly used to treat elderly patients with primary glenohumeral osteoarthritis (GHOA) and an intact rotator cuff. This is often done to avoid revision surgery in elderly patients for rotator cuff failure with anatomic total shoulder arthroplasty (TSA) despite traditionally good outcomes of TSA. We sought to determine whether there was a difference in outcomes in patients aged ≥70 years who received RTSA vs. TSA for GHOA. METHODS: A retrospective cohort study was conducted using data from a US integrated health care system's shoulder arthroplasty registry. Patients aged ≥70 years who underwent primary shoulder arthroplasty for GHOA with an intact rotator cuff were included (2012-2021). RTSA was compared with TSA. Multivariable Cox proportional hazard regression was used to evaluate all-cause revision risk during follow-up, whereas multivariable logistic regression was used to evaluate 90-day emergency department (ED) visits and 90-day readmissions. RESULTS: The final study sample comprised 685 RTSA patients and 3106 TSA patients. The mean age was 75.8 years (standard deviation, 4.6 years), and 43.4% of patients were men. After accounting for confounders, we observed no significant difference in all-cause revision risk for RTSA vs. TSA (hazard ratio, 0.79; 95% confidence interval [CI], 0.39-1.58). The most common reason for revision following RTSA was glenoid component loosening (40.0%). Over half of revisions following TSA were for rotator cuff tear (54.0%). No difference based on procedure type was observed in the likelihood of 90-day ED visits (odds ratio, 0.94; 95% CI, 0.71-1.26) and 90-day readmissions (odds ratio, 1.32; 95% CI, 0.83-2.09). CONCLUSION: RTSA and TSA for GHOA with an intact rotator cuff in patients aged ≥70 years had a similar revision risk, as well as a similar likelihood of 90-day ED visits and readmissions. Although revision risk was similar, the most common causes of revision were different, with rotator cuff tears in TSA patients and glenoid component loosening in RTSA patients.


Assuntos
Artroplastia do Ombro , Osteoartrite , Lesões do Manguito Rotador , Articulação do Ombro , Idoso , Masculino , Humanos , Feminino , Artroplastia do Ombro/efeitos adversos , Estudos de Coortes , Articulação do Ombro/cirurgia , Estudos Retrospectivos , Reoperação , Resultado do Tratamento , Osteoartrite/cirurgia , Osteoartrite/etiologia , Lesões do Manguito Rotador/cirurgia , Lesões do Manguito Rotador/etiologia , Amplitude de Movimento Articular
3.
Clin Orthop Relat Res ; 476(8): 1612-1619, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29621028

RESUMO

BACKGROUND: Corrective anterior reaming is an accepted method for addressing retroversion in a biconcave retroverted (Walch classification, type B2) glenoid in anatomic total shoulder arthroplasty. However, concern still exists regarding early glenoid component failure in the setting of severe retroversion, which may be related to loss of component containment and/or violation of subchondral bone resulting from reaming. The goal of this study was to determine what characteristics of B2 glenoids are less amenable to corrective reaming by virtually implanting anatomic glenoid components. QUESTIONS/PURPOSES: (1) How much medial reaming is required to correct the version of a B2 glenoid to an acceptable position? (2) Are glenoids with more severe retroversion (> 25°) at higher risk of component perforation than less retroverted glenoids? (3) Is correcting to 10° of retroversion associated with greater risk as compared with reaming to 15°? (4) How does corrective reaming affect the underlying bone density on the glenoid face of B2 glenoids? METHODS: A series of 71 patients with B2 glenoids (posterior subluxation of the humeral head with posterior bone loss) with CT scans who were indicated for shoulder arthroplasty were reviewed. Forty-four of 71 glenoids (62.5%) had < 25° of native retroversion. Anatomic glenoid implants were then virtually implanted using three-dimensional CT software that allows for preoperative shoulder arthroplasty planning to correct native retroversion to 15° or 10° of retroversion using both a central peg with an inverted triangle peg configuration or a keel. The amount of reaming of the anterior glenoid required to correct retroversion, perforation of peripheral pegs, or keel was compared. Additionally, assessment of the surface area of the glenoid that had poor bone density (defined as cancellous bone under the subchondral plate) was analyzed by the software after correction. RESULTS: Correction to 15° of retroversion required 5 ± 3 mm of reaming, and correction to 10° of retroversion required 8 ± 3 mm of reaming to obtain at least 80% seating. Peripheral peg perforation with correction to 15° occurred in 15 of 27 (56%) glenoids with > 25° of retroversion compared with 10 of 44 (23%) of glenoids with < 25° of retroversion (relative risk [RR], 2.4; 95% confidence interval [CI], 1.3-4.6; p = 0.006). There was no difference in perforation with keeled components. Increased correction to 10° did not increase the risk of component perforation. When correction to 15°, glenoids with higher native version (> 25°) had a greater risk of poor bone quality support (10 of 27 [37%]) when compared with glenoids with less version (four of 44 [9%]; RR, 4.1; 95% CI, 1.5-12.8; p = 0.006). Increased correction resulted in 13 of 27 (48%) glenoids with version > 25° having poor bone density versus 10 of 44 (23%) with ≤ 25° of version (RR, 2.1; 95% CI, 1.1-4.1; p = 0.028). CONCLUSIONS: There is a high risk of vault perforation after corrective reaming. Glenoid retroversions > 25° are at a higher risk of having poor bone quality supporting the component. CLINICAL RELEVANCE: When contemplating options for patients with severe retroversion, surgeons should consider alternatives other than corrective reaming if achieving normal glenoid version is desired.


Assuntos
Artroplastia do Ombro/efeitos adversos , Retroversão Óssea/cirurgia , Cavidade Glenoide/transplante , Complicações Intraoperatórias/etiologia , Perfuração Espontânea/etiologia , Idoso , Idoso de 80 Anos ou mais , Artroplastia do Ombro/métodos , Retroversão Óssea/patologia , Simulação por Computador , Feminino , Cavidade Glenoide/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco
4.
J Shoulder Elbow Surg ; 27(2): 339-349, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29332666

RESUMO

BACKGROUND: Our study purpose was to determine the optimal glenoid and humeral reverse shoulder arthroplasty (RSA) component design and position in osteoarthritic shoulders with severe glenoid retroversion deformities. METHODS: Computed tomography scans from 10 subjects were analyzed with advanced software including RSA range of motion (ROM) analysis. Variables included glenoid component retroversion of 0°, 5°, 10°, 15°, and 20° and baseplate lateralization of 0, 5, and 10 mm. Humeral variables included 135°, 145°, and 155° angle of inclination (AOI) combined with variable humeral offset. RESULTS: Glenoid component lateralization had the greatest influence on ROM. In comparing each ROM direction among all lateralization options independently, there were significantly greater adduction, abduction, external rotation, extension, and flexion motions with progressively greater lateralization. Internal rotation motion was greater at 10 mm only. In analyzing the effects of glenoid version independently, no differences in adduction or abduction ROM were seen. With greater retroversion, decreased external rotation and extension motion was noted; however, greater internal rotation and flexion motion was seen with the exception of flexion at 10 mm of lateralization. For adduction, external rotation, and extension, a more valgus AOI resulted in less ROM at each progressively greater AOI independent of humeral lateralization. Internal rotation and flexion motions were greater with a more varus AOI but not significant between each inclination angle. Abduction ROM was maximized with a more valgus AOI. Humeral lateralization had no effect on ROM. CONCLUSIONS: In the setting of RSA for advanced glenoid osteoarthritic deformities, optimal ROM is achieved with 10-mm baseplate lateralization and neutral to 5° of retroversion mated to a humeral implant with a varus (135°) inclination angle.


Assuntos
Artroplastia do Ombro/métodos , Imageamento Tridimensional , Amplitude de Movimento Articular/fisiologia , Síndrome de Colisão do Ombro/diagnóstico , Articulação do Ombro/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Síndrome de Colisão do Ombro/fisiopatologia , Síndrome de Colisão do Ombro/cirurgia , Articulação do Ombro/cirurgia
5.
J Shoulder Elbow Surg ; 27(6S): S58-S64, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29501223

RESUMO

BACKGROUND: This study describes the short-term functional and radiographic outcomes after total shoulder arthroplasty (TSA) in shoulders with a B2 glenoid deformity addressed with corrective reaming. METHODS: We conducted a retrospective series of consecutive patients who underwent TSA with a Walch B2 glenoid quantified by computed tomography scan. All glenoid deformities were addressed using partially corrective glenoid reaming. Radiographic and functional outcome measures, including scores on the visual analog scale for pain, American Shoulder and Elbow Standardized Shoulder Assessment, and Simple Shoulder Test were collected. RESULTS: Functional outcome scores were available for 59 of 92 eligible subjects (64%) at a mean of 50 months. The mean preoperative retroversion measured 18° (range, -1° to 36°), superior inclination was 8° (range, -11° to 27°), and posterior subluxation was 67% (range, 39%-91%). Mean visual analog scale improved from 7.4 to 1.4, the American Shoulder and Elbow Shoulder Standardized Assessment improved from 35.4 to 84.3, and the SST improved from 4.5 to 9.1. Radiographs were evaluated at a mean of 31 months: 38 had no glenoid radiolucent lines, 13 glenoids had grade 1, 2 had grade 2, and 5 had grade 3 lucencies. There was no difference in the rate of progression of glenoid radiolucencies between shoulders with a preoperative glenoid version of ≤20° (27.8%) compared with glenoids with >20° of retroversion (22.7%, P = .670). No shoulders were revised due to glenoid loosening or instability. CONCLUSION: TSA with partial corrective glenoid reaming in selected shoulders with a B2 glenoid deformity resulted in excellent functional and radiographic outcomes at short-term follow-up, with a low risk of revision surgery.


Assuntos
Artroplastia do Ombro/métodos , Cavidade Glenoide/cirurgia , Articulação do Ombro/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Artroplastia do Ombro/efeitos adversos , Feminino , Humanos , Luxações Articulares/etiologia , Masculino , Pessoa de Meia-Idade , Osteoartrite/cirurgia , Medição da Dor , Radiografia , Reoperação , Estudos Retrospectivos , Articulação do Ombro/diagnóstico por imagem , Articulação do Ombro/fisiopatologia , Tomografia Computadorizada por Raios X
6.
J Shoulder Elbow Surg ; 27(5): 863-870, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29289492

RESUMO

BACKGROUND: The purpose of this study was to determine the effect of humeral articular component positioning on changes in patient-reported outcomes after anatomic total shoulder arthroplasty. METHODS: This was a retrospective series of consecutive patients at 2 high-volume referral centers. The study included patients with (1) a preoperative and postoperative radiograph demonstrating a perfect or nearly perfect profile of the humerus and implant and (2) Simple Shoulder Test, visual analog scale for pain, and American Society of Shoulder and Elbow Surgeons (ASES) Standardized Shoulder Assessment scores preoperatively and at greater than 2 years postoperatively. Head height, head diameter, tuberosity-to-head height distance, inclination, and medial offset of the center of rotation (COR) were measured preoperatively and postoperatively. Distance and direction from the ideal COR to the reconstructed center of rotation was measured. Measurements were correlated with improvement in functional outcomes. RESULTS: The study included 95 patients, aged 66 ± 9 years, with a mean follow-up of 4.3 ± 1.7 years. An a priori power analysis suggested that a sample size of 95 patients provided 80% power to detect correlations of R2 = 0.07. The COR shift was >2 mm in 62% of patients and >4 mm 15%. Thirty-two percent had a change of ASES of <21 points. On multivariate analysis, there were no significant associations between any change in measured prosthetic radiographic parameters and changes in the visual analog scale, Simple Shoulder Test, or ASES scores (P > .05). CONCLUSION: In this retrospective analysis of total shoulder arthroplasty in which most components were well positioned, humeral component positioning did not associate with change in postoperative outcomes. These findings should be prospectively confirmed.


Assuntos
Artroplastia do Ombro/métodos , Úmero/diagnóstico por imagem , Osteoartrite/cirurgia , Dor Pós-Operatória/diagnóstico , Amplitude de Movimento Articular/fisiologia , Articulação do Ombro/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Úmero/cirurgia , Masculino , Pessoa de Meia-Idade , Osteoartrite/diagnóstico , Período Pós-Operatório , Desenho de Prótese , Radiografia , Estudos Retrospectivos , Articulação do Ombro/cirurgia , Resultado do Tratamento , Escala Visual Analógica
7.
J Shoulder Elbow Surg ; 27(6S): S17-S23, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29776469

RESUMO

BACKGROUND: The Patient-Reported Outcomes Measurement Information System (PROMIS) is being used to assess outcomes in many patient populations despite limited validation. The purpose of this study was to investigate the relationship between American Shoulder and Elbow Surgeons (ASES) and Simple Shoulder Test (SST) scores and PROMIS Physical Function (PF) and Upper Extremity (UE) function scores collected preoperatively in patients undergoing rotator cuff repair. METHODS: This cross-sectional study analyzed 164 consecutive patients undergoing arthroscopic rotator cuff repair. Study inclusion required preoperative completion of the ASES and SST evaluations, as well as the PROMIS PF, UE, and Pain Interference computerized adaptive tests. Descriptive statistics were produced, and Pearson correlation coefficients were calculated between each of the outcome measures. RESULTS: Average PROMIS UE scores indicated greater impairment than PROMIS PF scores (34 vs 44). Three percent of patients reached the PROMIS UE ceiling score of 56. PROMIS PF scores demonstrated a weak correlation with ASES scores (r = 0.43, P < .001) and a moderate correlation with SST scores (r = 0.51, P < .001). PROMIS UE scores demonstrated a moderate correlation with both ASES scores (r = 0.59, P < .001) and SST scores (r = 0.62, P < .001). PROMIS Pain Interference scores demonstrated weak negative correlations with both ASES scores (r = -0.43, P < .001) and SST scores (r = -0.41, P < .001). Patients answered fewer questions on average using the PROMIS PF and UE instruments as compared with the ASES and SST instruments. CONCLUSION: PROMIS UE scores indicate greater impairment and demonstrate a stronger correlation with the legacy shoulder scores than PROMIS PF scores in patients with symptomatic rotator cuff tears. PROMIS computerized adaptive tests allow for more efficient patient-reported outcome data collection compared with traditional outcome scores.


Assuntos
Medidas de Resultados Relatados pelo Paciente , Lesões do Manguito Rotador/fisiopatologia , Lesões do Manguito Rotador/cirurgia , Extremidade Superior/fisiopatologia , Adolescente , Adulto , Idoso , Artroplastia , Artroscopia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento , Adulto Jovem
8.
JBJS Case Connect ; 11(3)2021 09 17.
Artigo em Inglês | MEDLINE | ID: mdl-34534140

RESUMO

CASES: Two patients presented with medial chest pain and deformity after high-speed motor vehicle accidents (MVAs) in which they were restrained drivers. Physical examination revealed retraction of the pectoralis major from the sternum on resisted adduction and internal rotation of the arm. MRI confirmed tears of the pectoralis major from the sternal origin. Both patients underwent delayed surgical repair with excellent results. CONCLUSION: Tears of the pectoralis major at the sternal origin are rare injuries that can result in significant deformity and pain. Surgical repair, even in a delayed fashion, can result in excellent patient outcomes.


Assuntos
Músculos Peitorais , Traumatismos dos Tendões , Humanos , Músculos Peitorais/lesões , Músculos Peitorais/cirurgia , Ruptura/cirurgia , Cintos de Segurança/efeitos adversos , Esterno/cirurgia , Traumatismos dos Tendões/cirurgia
9.
JSES Int ; 4(3): 638-643, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32939499

RESUMO

BACKGROUND: To address severe posterior subluxation associated with the Walch B2 glenoid deformity, the eccentricity of the prosthetic humeral head can be reversed, allowing the humerus to remain in a relatively posterior position while the prosthetic humeral head remains well-centered on the glenoid. This study describes the short-term outcomes after anatomic total shoulder arthroplasty (TSA) using this technique. METHODS: We retrospectively reviewed a consecutive series of patients with a B2 glenoid who underwent TSA with the prosthetic eccentric humeral head rotated anteriorly for excessive posterior subluxation noted intraoperatively. Medical records were reviewed for visual analog scale (VAS), American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES), and Simple Shoulder Test (SST) scores. Final radiographs were analyzed for instability, lesser tuberosity osteotomy healing, and glenoid loosening. RESULTS: Twenty patients were included with outcome scores at a mean of 48 months. Mean VAS (P < .0001), ASES (P < .0001), and SST (P < .0001) scores improved significantly. Using the Lazarus classification for glenoid loosening, 5 patients had grade 1 lucency and 2 had grade 2 lucency at a mean of 24 months' follow-up. The remaining 13 patients had no glenoid lucencies. Radiographic decentering was reduced from a mean of 9.9% ± 5.7% preoperatively to 0.5% ± 3.0% postoperatively (P < .001). There were no cases of lesser tuberosity repair failures or revision surgery. CONCLUSION: TSA in patients with a B2 glenoid with a reversed, anterior-offset humeral head to address residual posterior subluxation resulted in excellent functional outcomes at short-term follow-up with improvement in humeral head centering. Early radiographic follow-up suggests low risks of progressive glenoid lucencies and component loosening.

10.
J Am Acad Orthop Surg ; 27(5): 156-165, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30335631

RESUMO

Degenerative rotator cuff tears are the most common cause of shoulder pain and have a strong association with advanced aging. Considerable variation exists in surgeons' perceptions on the recommended treatment of patients with painful rotator cuff tears. Natural history studies have better outlined the risks of tear enlargement, progression of muscle degeneration, and decline in the function over time. This information combined with the known factors potentially influencing the rate of successful tendon healing such as age, tear size, and severity of muscle degenerative changes can be used to better refine appropriate surgical indications. Although conservative treatment can be successful in the management of many of these tears, risks to nonsurgical treatment also exist. The application of natural history data can stratify atraumatic degenerative tears according to the risk of nonsurgical treatment and better identify tears where early surgical intervention should be considered.


Assuntos
Procedimentos Ortopédicos/métodos , Lesões do Manguito Rotador/cirurgia , Manguito Rotador/fisiopatologia , Idoso , Envelhecimento , Progressão da Doença , Feminino , Humanos , Masculino , Manguito Rotador/patologia , Lesões do Manguito Rotador/complicações , Lesões do Manguito Rotador/patologia , Dor de Ombro/etiologia
11.
Orthop J Sports Med ; 5(9): 2325967117728019, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28975132

RESUMO

BACKGROUND: The delayed management of patients with shoulder instability may increase the prevalence and severity of concomitant intra-articular shoulder injuries resulting from persistent subluxations and dislocations. HYPOTHESIS: Patients with a longer delay from the initial dislocation event to undergoing magnetic resonance imaging (MRI) or magnetic resonance arthrography will demonstrate more subluxations or dislocations and a greater amount of intra-articular shoulder damage. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: We performed a retrospective review of 89 patients from a single institution with clinically and radiographically confirmed primary traumatic anterior shoulder dislocations. Patients were divided into 2 groups: those undergoing MRI less than 6 months (n = 44; LT6) or greater than 6 months (n = 45; GT6) from the initial dislocation event. The MRI assessment included evaluation of soft tissue injuries, including the labrum, capsule, rotator cuff, and cartilage damage severity along with bone loss. RESULTS: The delayed MRI group (GT6) demonstrated a greater degree of intra-articular abnormalities compared to the early MRI group (LT6). A greater percentage of superior labral anterior-posterior (SLAP) tears (58% vs 34%, respectively) and cartilage damage (73% vs 27%, respectively) was present in the GT6 group compared to the LT6 group. Cartilage damage was 18% mild, 7% moderate, and 2% severe for the LT6 group as compared to 38% mild, 31% moderate, and 4% severe for the GT6 group. Additionally, more recurrent shoulder dislocations were seen in the GT6 group (n = 6) compared to the LT6 group (n = 2). In the LT6 group, there were more rotator cuff tears (50% vs 24%, respectively) and capsular tears (25% vs 9%, respectively) than the GT6 group. There was no difference in anterior glenoid bone loss, glenoid version, or humeral head subluxation between the 2 groups. CONCLUSION: Patients who undergo MRI greater than 6 months from the time of primary or initial shoulder dislocation had significantly more recurrent shoulder instability events and demonstrated a greater incidence and severity of intra-articular abnormalities, including SLAP tears, posterior labral tears, and anterior glenoid cartilage damage.

12.
Orthop Rev (Pavia) ; 8(1): 6113, 2016 Mar 21.
Artigo em Inglês | MEDLINE | ID: mdl-27114806

RESUMO

Total elbow arthroplasty (TEA) is utilized in the treatment of rheumatoid and post-traumatic elbow arthritis. TEA is a relatively low volume surgery in comparison to other types of arthroplasty and therefore little is known about current surgical utilization, patient demographics and complication rates in the United States. The purpose of our study is to evaluate the current practice trends and associated in-patient complications of TEA at academic centers in the United States. We queried the University Health Systems Consortium administrative database from 2007 to 2011 for patients who underwent an elective TEA. A descriptive analysis of demographics was performed which included patient age, sex, race, and insurance status. We also evaluated the following patient clinical benchmarks: hospital length of stay (LOS), hospital direct cost, in-hospital mortality, complications, and 30-day readmission rates. Our cohort consisted of 3146 adult patients (36.5% male and 63.5% female) with an average age of 58 years who underwent a total elbow arthroplasty (159 academic medical centers) in the United States. The racial demographics included 2334 (74%) Caucasian, 285 (9%) black, 236 (7.5%) Hispanic, 16 (0.5%) Asian, and 283 (9%) other patients. The mean LOS was 4.2±5 days and the mean total direct cost for the hospital was 16,300±4000 US Dollars per case. The overall inpatient complication rate was 3.1% and included mortality <1%, DVT (0.8%), re-operation (0.5%), and infection (0.4%). The 30-day readmission rate was 4.4%. TEA is a relatively uncommon surgery in comparison to other forms of arthroplasty but is associated with low in-patient and 30-day perioperative complication rate. Additionally, the 30-day readmission rate and overall hospital costs are comparable to the traditional total hip and knee arthroplasty surgeries.

13.
Am J Orthop (Belle Mead NJ) ; 42(9): 420-2, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24078967

RESUMO

We report the case of a 56-year-old woman who had severe leg pain and whose radiographs initially suggested metastatic carcinoma, lymphoma, osteogenic sarcoma, or adamantinoma. Results of multiple biopsies confirmed a diagnosis of Rosai-Dorfman disease, which typically presents in children and young adults (mean age at onset, 20 years).


Assuntos
Neoplasias Ósseas/diagnóstico , Histiocitose Sinusal/diagnóstico , Tíbia/patologia , Neoplasias Ósseas/diagnóstico por imagem , Neoplasias Ósseas/patologia , Diagnóstico Diferencial , Feminino , Histiocitose Sinusal/diagnóstico por imagem , Histiocitose Sinusal/patologia , Humanos , Pessoa de Meia-Idade , Radiografia , Tíbia/diagnóstico por imagem
14.
J Pediatr Surg ; 45(4): 729-34, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20385279

RESUMO

BACKGROUND: Necrotizing enterocolitis (NEC) is the leading surgical cause of death in premature infants. We have accumulated evidence supporting a role for heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) in protection of the intestines from NEC. The aim of the current study was to evaluate the effect of loss-of-function of endogenous HB-EGF on susceptibility to NEC. METHODS: Neonatal HB-EGF((-/-)) knockout (KO) mice and their HB-EGF((+/+)) wild-type (WT) counterparts were exposed to experimental NEC. An additional group of HB-EGF KO pups were also exposed to NEC but had HB-EGF added to their formula. To examine gut barrier function, HB-EGF KO and WT pups received intragastric fluorescein isothiocyanate-labeled dextran (FITC dextran) under basal and stressed conditions, and serum FITC dextran levels were measured. RESULTS: The WT mice had an incidence of NEC of 53%, whereas HB-EGF KO mice had a significantly increased incidence of NEC of 80% (P = .04). Importantly, administration of exogenous HB-EGF to HB-EGF KO pups significantly reduced the incidence of NEC to 45% (P = .04). Heparin-binding EGF KO mice had significantly increased intestinal permeability compared to WT mice under basal and stressed conditions. CONCLUSIONS: Our results provide evidence that loss of the HB-EGF gene increases susceptibility to NEC and that administration of exogenous HB-EGF reverses this susceptibility.


Assuntos
Enterocolite Necrosante/genética , Deleção de Genes , Peptídeos e Proteínas de Sinalização Intercelular/genética , Animais , Animais Recém-Nascidos , Enterocolite Necrosante/prevenção & controle , Predisposição Genética para Doença , Fator de Crescimento Semelhante a EGF de Ligação à Heparina , Peptídeos e Proteínas de Sinalização Intercelular/uso terapêutico , Mucosa Intestinal/metabolismo , Camundongos , Camundongos Knockout , Permeabilidade
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