Histopathological Classifications of Oral Leukoplakia and its Relation to Cell Proliferative Activity: A Case Series.

AIM: This study relates the average number of nucleolar organizing regions (NORs) obtained in a series of cases of oral leukoplakia, with three methods of histopathological classification of such lesion. MATERIALS AND METHODS: This is a histopathological-histochemical laboratory cross-sectional study. The 18 cases of leukoplakia analyzed were filed at Pathology Service of the Biological Sciences Institute of the University of Passo Fundo, Rio Grande do Sul, Brazil (SDH/ICB/UPF) (2017 and 2018), from which epidemiological data were extracted. New histological sections were performed for impregnation by the argyrophilic nucleolar organizer regions (AgNOR) technique. The histopathological slides were analyzed by photon microscopy (1,000×), and the nuclei of 100 epithelial cells were photographed to count the number of NORs. Three methods were used for the lesions' histopathological classification [World Health Organization (WHO), Brothwell, and binary system]. The means of NORs were compared with the three histopathological classifications by means of the t or analysis of variance (ANOVA) statistical tests, at a significance level of 5%. RESULTS: According to the WHO classification method, most cases (11-61.1%) had a moderate classification. Evaluations by the Brothwell method showed moderate and mild classification in 50 and 38.9% of cases, respectively. According to the binary system, most cases (10-55.6%) had low risk. The average NORs found in 100 nuclei of each of the 18 lesions ranged from 2 to 4. When crossing the average NORs with the histopathological classification methods of the lesions by means of the t test or ANOVA, no significant relationship was noted. CONCLUSION: The average of NORs is not associated with the histological classifications of leukoplakias. Thus, the AgNOR method should be used with caution when differentiating different histological grades of leukoplakias. CLINICAL SIGNIFICANCE: The AgNOR method should be used with caution to determine the clinical treatment of oral leukoplakias, since no agreement was observed between this method and the histopathological classifications available for such lesion.

Self-Perception of Teeth Alignment and Colour in Adolescents: A Cross-sectional Study.

OBJECTIVE: This study aimed to evaluate the prevalence and factors associated with self-perception of teeth alignment and colour in adolescents. METHODS: This cross-sectional study was carried out in public and private schools in Passo Fundo, Brazil. A representative sample of students aged 15 to 19 years were included. The outcome of this study was self-perception of teeth alignment and colour according to selected items from a structured and validated questionnaire (the Child's and Parent's Questionnaire about Teeth Appearance). Bivariate and multivariable analysis, using Poisson regression with robust variance, were used. A P value <.05 was established for statistical significance. RESULTS: The study included 736 adolescents. The worst self-perception of teeth alignment and colour was observed in 46.5% (n = 342) of the adolescents. Nonsmokers presented a prevalence ratio (PR) 29% lower (95% CI, 0.57-0.89) for the worst self-perception of teeth alignment and colour when compared to smokers/former smokers. Adolescents with highly educated mothers presented a lower prevalence of negative self-perception than those with mothers with a low level of education (PR: 0.66; 95% CI, 0.51-0.86). Presence of orthodontic treatment with (PR: 0.76; 95% CI, 0.62-0.94) or without (PR: 0.61; 95% CI, 0.46-0.76) tooth whitening were associated with better self-perception of teeth alignment and colour. CONCLUSIONS: Exposure to smoking and lower maternal level of education were associated with worse self-perception of teeth alignment and colour in adolescents. A history of orthodontic treatment with or without tooth whitening was associated with a lower concern with aesthetics.

Prevalence of tooth loss and associated factors in institutionalized adolescents: a cross-sectional study.

This study aimed to assess the prevalence of tooth loss and associated factors in institutionalized adolescents. This cross-sectional study included 68 male adolescents incarcerated from Socio-Educational Assistance Center (CASE) aged between 15 and 19 years. Questionnaires were applied individually to assess sociodemographical, economical, medical, behavioral and oral health self-perception variables. All present teeth were evaluated by Decay, Missing, Filling (DMF) Index. The prevalence of tooth loss was analyzed in individuals with ≥1 tooth loss. Associations between tooth loss and exposure variables studied were analyzed by Poisson Regression with robust variance estimation. The prevalence of tooth loss was 47.06%. First molars in the mandible and maxilla and central incisor in the maxilla were the most absent teeth. In the multivariate model, number of decayed teeth, and those that reported daily use of medication were associated with higher tooth loss. Besides, tooth loss was associated with decayed tooth and daily use of medication. Oral health promotion and treatment should be implemented in these institutions to reduce the prevalence of dental loss in these adolescents.

Association between history of orthodontic treatment and sociodemographic factors in adolescents.

The aim of this study was to assess history of orthodontic treatment and its determinants in adolescents. This was a crosssectional study conducted in the city of Passo Fundo, Brazil, on a representative sample of adolescents aged 15 to 19 years, regularly enrolled in 20 high schools. A structured questionnaire was applied to assess demographic, behavioral and health variables. The association between history of orthodontic treatment and the dependent variables was analyzed by the chi-square test or Fisher's exact test. Additionally, multivariate regression with robust variance was performed. A total 736 students were examined and interviewed, of whom 57. 6% had undergone orthodontic treatment, while 42. 4% had not. In the multivariable analysis, the following variables were significantly associated with history of orthodontic treatment: female (PR= 1. 26; 95% CI: 1. 11-1. 43), white (PR= 1. 32; 95% CI: 1. 11-1. 56), mothers with higher level of education (PR=1. 49; 95% CI: 1. 28 -1. 74), tooth loss (PR=1. 21; 95% CI: 1. 06-1. 39), and concern about oral health (PR=0. 69; 95% CI: 0. 61-0. 78). Attending a private school was not significantly associated with history of orthodontic treatment (p>0. 05). This study found a high rate for history of orthodontic treatment among adolescents, associated with gender, ethnicity, adolescent's mother with higher education, and tooth loss. Concern about oral health was a protective factor for orthodontic treatment.

Esse estudo objetivou verificar o histórico de tratamento ortodontico e seus fatores associados. Esse estudo transversal foi conduzido na cidade de Passo Fundo, Brasil, com uma amostra representativa dos adolescentes regularmente matriculados no ensino médio, com idades entre 15 e 19 anos, de 20 escolas. Um questionário estrutura foi aplicado para acessar variáveis demográficas, comportamentais e de saúde. As associações entre histórico de tratamento ortodontico e as variáveis independentes foram analisadas pelos testes de qui-quadrado ou exato de Fisher. Além disso, regressão multivariada com variáncia robusta foi realizada. 736 estudantes foram examinados e entrevistados. Tratamento ortodontico foi realizado por 57,6% dos adolescentes, enquanto que 42,4% dos participantes nao o mencionaram. Na análise multivariada, as seguintes variáveis estiveram significativamente associadas com histórico de tratamento ortodôntico: sexo feminino (PR= 1,26; 95%CI: 1,11-1,43), branco (PR= 1,32; 95%CI: 1,11-1,56), mâes com alto nivel educacional (PR=1,49; 95%CI: 1,28-1,74), perda dentária (PR=1,21; 95%CI: 1,06-1,39) epreocupaçâo com a saúde bucal (PR=0,69; 95%CI: 0,61-0,78). Ir a uma escola fiprivada nao esteve significativamente associado com histórico de tratamento ortodôntico (p>0,05). Esse estudo demonstrou que altos niveis de histórico de tratamento ortodôntico são encontrados em adolescentes e isso está associado com sexo, etnia, alta escolaridade da mae do adolescente eperda dentária. Preocupaçâo com a saúde bucal mostrou-se como um fator protetorpara o tratamento ortodôntico.

Fixed and on-demand regimens of acetaminophen in periodontal surgery: randomized clinical trial

Aim: to evaluate the clinical efficacy of an acetaminophen analgesic by comparing its prescription in fixed versus ondemand schedules after periodontal surgery. The hypothesis of the study was that the fixed regimen would be more effective than the on-demand regimen for postoperative analgesics following periodontal surgery. Methods: An open randomized clinical trial was conducted. The 68 patients who needed total flap surgery to restore supracrestal tissue attachment or surgical treatment of periodontitis were randomized". Visual Analogue Scale was used to assess pain. The fixed group (n = 34) received 500 mg of acetaminophen every 4 hours for 2 days. The on-demand group (n = 34) was instructed to use the acetaminophen "as needed," at intervals of no less than 4 hours between doses. Ibuprofen was the rescue medication for both groups. Pain scores and medication use were recorded 2, 6, 12, 24 and 48 hours after the surgical procedure. The study was registered at the Brazilian Registry of Clinical Trials under RBR-7wv259. Results: The two groups did not differ in relation to the frequency or the intensity of pain in a 48-hour period (n=20 in the fixed group, and n=22 in the on-demand group), or even in the intention-to-treat (n=34 in each group). Individuals who experienced moderate to severe pain used rescue medication more frequently in both groups. No adverse events were reported. Conclusion: Both regimens were effective in controlling postoperative pain after periodontal surgery

Aplicação de práticas integrativas e complementares na odontologia / Application of complementary and integrative practices in dentistry

A incorporação de novas tecnologias e métodos para proporcionar um atendimento odontológico mais confortável, humano e menos invasivo, propiciou o uso de terapias alternativas e complementares em Odontologia. Objetivo: revisar a literatura e assim fornecer ao cirurgião-dentista maiores informações a respeito dos recursos alternativos e complementares utilizados no consultório odontológico. Materiais e Métodos: A pesquisa foi realizada utilizando termos Decs e operadores boleanos. As bases de dados consultadas foram Pubmed, Lilacs, Scielo e Google Scholar, no ano de 2020, e após aplicação dos critérios de elegibilidade, foram selecionados 65 estudos, dentre estudos clínicos randomizados e não-randomizados, estudos observacionais, revisões sistemáticas e não ­ sistemáticas. Resultados e Discussão: Destaca-se as terapias: Acupuntura, Crioterapia, Fitoterapia, Hipnose, Homeopatia, Laserterapia, Massoterapia, Musicoterapia, Ozonioterapia, Terapia fotodinâmica e Toxina Botulínica, nas suas diversas pluralidades de aplicação, não somente para a área odontológica, mas na integralização com diversos campos, atuando no físico e psíquico. Conclusão: Diante dos achados, pode-se concluir que grande parte das terapias complementares são bem empregadas em Odontologia. Entretanto, mais evidências científicas são essenciais para o desempenho de tais práticas. Isto as tornará eficazes e seguras, tanto na atenção à saúde em âmbito público, quanto privado, permitindo à população brasileira beneficiar-se das terapias como alternativas eficientes e de baixo custo.

The incorporation of new technologies and methods to provide a more comfortable, humane and less invasive dental care, favored the use of alternative and complementary therapies in Dentistry. Objective: to review the literature and thus provide the dentist with more information about alternative and complementary resources used in the dental office. Materials and Methods: The research was carried out using terms Decs and Boolean operators. The databases consulted were Pubmed, Lilacs, Scielo and Google Scholar, in 2020, and after applying the eligibility criteria, 65 studies were selected, among randomized and non-randomized clinical studies, observational studies, systematic reviews and non- systematic. Results and Discussion: Therapies stand out: Acupuncture, Cryotherapy, Phytotherapy, Hypnosis, Homeopathy, Laser Therapy, Massage Therapy, Music Therapy, Ozone Therapy, Photodynamic Therapy and Botulinum Toxin, in their diverse application areas, not only in the dental field, but in integration with several fields, working in the physical and psychic. Conclusion: Given the findings, it can be concluded that most complementary therapies are well used in dentistry. However, more scientific evidence is essential for the performance of such practices. This will make them effective and safe, both in public and private health care, allowing the Brazilian population to benefit from therapies as efficient and low-cost alternatives.

Association between history of orthodontic treatment and sociodemographic factors in adolescents / Associação entre histórico de tratamento ortodôntico e fatores sociodemográficos em adolescentes

The aim of this study was to assess history of orthodontic treatment and its determinants in adolescents. This was a crosssectional study conducted in the city of Passo Fundo, Brazil, on a representative sample of adolescents aged 15 to 19 years, regularly enrolled in 20 high schools. A structured questionnaire was applied to assess demographic, behavioral and health variables. The association between history of orthodontic treatment and the dependent variables was analyzed by the chisquare test or Fisher's exact test. Additionally, multivariate regression with robust variance was performed. A total 736 students were examined and interviewed, of whom 57.6% had undergone orthodontic treatment, while 42.4% had not. In the multivariable analysis, the following variables were significantly associated with history of orthodontic treatment: female (PR= 1.26; 95% CI: 1.11 ­ 1.43), white (PR= 1.32; 95% CI: 1.11 ­ 1.56), mothers with higher level of education (PR=1.49; 95% CI: 1.28 ­ 1.74), tooth loss (PR=1.21; 95% CI: 1.06 ­ 1.39), and concern about oral health (PR=0.69; 95% CI: 0.61 ­ 0.78). Attending a private school was not significantly associated with history of orthodontic treatment (p>0.05). This study found a high rate for history of orthodontic treatment among adolescents, associated with gender, ethnicity, adolescent's mother with higher education, and tooth loss. Concern about oral health was a protective factor for orthodontic treatment (AU)

Esse estudo objetivou verificar o histórico de tratamento ortodôntico e seus fatores associados. Esse estudo transversal foi conduzido na cidade de Passo Fundo, Brasil, com uma amostra representativa dos adolescentes regularmente matricu lados no ensino médio, com idades entre 15 e 19 anos, de 20 escolas. Um questionário estrutura foi aplicado para acessar variáveis demográficas, comportamentais e de saúde. As associações entre histórico de tratamento ortodôntico e as variáveis independentes foram analisadas pelos testes de quiquadrado ou exato de Fisher. Além disso, regressão multivariada com variância robusta foi realizada. 736 estudantes foram examinados e entrevistados. Tratamento ortodôntico foi reali zado por 57,6% dos adolescentes, enquanto que 42,4% dos participantes não o mencionaram. Na análise multivariada, as seguintes variáveis estiveram significativamente associadas com histórico de tratamento ortodôntico: sexo feminino (PR= 1,26; 95%CI: 1,11 ­ 1,43), branco (PR= 1,32; 95%CI: 1,11 ­ 1,56), mães com alto nível educacional (PR=1,49; 95%CI: 1,28 ­ 1,74), perda dentária (PR=1,21; 95%CI: 1,06 ­ 1,39) e preocupação com a saúde bucal (PR=0,69; 95%CI: 0,61 ­ 0,78). Ir a uma escola privada não esteve significativamente associado com histórico de tratamento ortodôntico (p>0,05). Esse estudo demonstrou que altos níveis de histórico de tratamento ortodôntico são encontrados em adolescentes e isso está associado com sexo, etnia, alta escolaridade da mãe do adolescente e perda dentária. Preocupação com a saúde bucal mostrouse como um fator protetor para o tratamento ortodôntico (AU)