Two new triterpenoids from the fruits of Aphanamixis polystachya.

Two new triucallane triterpenoids, polystanin F (1) and polystanin G (2), along with eight known compounds (3-10) were isolated from the fruits of Aphanamixis polystachya. Their structures were established on the basis of extensive spectroscopic analysis. Moreover, eight compounds were evaluated for their in vitro cytotoxicity against three cancer cell lines (liver cancer RT112, colon cancer HCT-116 and breast cancer M231) using the MTT method. Compound 7 showed significant cytotoxic activity against HCT-116 with IC50 1.27 µM.

Effect of "green technology-institution" collaborative innovation on ecological efficiency-the moderating role of fiscal decentralization.

With the tightening of resource constraints and the proposal of the Chinese High-quality Development strategy, innovation-driven has emerged as a new option to balance economic progress with environmental protection. The paper takes Chinese inter-provincial panel data from 2007 to 2017 as a research sample and is based on a spatial Durbin model, investigating the association among green technology innovation (GTI), "green technology-institution" collaborative innovation, and ecological efficiency (EE), while fiscal decentralization is discussed as a moderating factor. According to the results, "green technology-institution" collaborative innovation is positively promoting ecological efficiency and causing spatial spillovers if the economic distance is taken into account. Compared with the single role of green technology innovation, collaborative innovation has a greater role in improving ecological efficiency. Among them, to improve ecological efficiency, it is best to develop green technology innovation and encourage production institutions in a coordinated manner. According to the moderating effect, fiscal decentralization moderates the impact of innovation collaboration on ecological efficiency in a negative way. Therefore, balancing the decentralization of local fiscal expenditures is important to promoting China's ecological efficiency. In addition, China should purposefully promote the degree of synergy between green technology innovation and related institutions for enhancing eco-efficiency.

Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells.

Two new sesquiterpenoids, including a kessane-type sesquiterpenoid (1) and one bisabolane derivative (2), together with fourteen known sesquiterpenoids (3-16), were isolated from the roots and rhizomes of Valeriana amurensis. The structures of new compounds were established on the basis of extensive spectroscopic analysis. All isolates were evaluated for their effects on nerve growth factor (NGF)-mediated neurite outgrowth in pheochromocytoma (PC12) cells. As a results, four compounds including 10-12 and 15 showed potent promoting effects at the concentration of 10 µM on NGF-induced neurite outgrowth in PC12 cells with the differentiation rate of 11.84%, 12.21%, 13.77% and 12.16%, respectively.