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Arq Neuropsiquiatr ; 61(2A): 226-33, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12806501

RESUMO

We carried out this work with the purpose of studying the effects of protein and vitamin B deficiency on the morphologic and quantitative aspects of the myenteric plexus of the descending colon of adult Rattus norvegicus. Twenty-eight rats were divided in two groups, one of them receiving chow with 22% protein level (control) and the other fed with chow having 8% protein level without vitamin B supplementation, during 120 days. Whole-mounts of the descending colon were prepared and stained with Giemsa, NADH-diaphorase and NADPH-diaphorase. The undernourished rats had a body weight 11.84% less than the control group. Relative to the controls, the experimental group had a colonic area 48% smaller, 51.9% less Giemsa-stained neurons, 28.3% less NADH-diaphorase positive neurons and 24.2% less NADPH-diaphorase positive neurons.


Assuntos
Colo/inervação , Plexo Mientérico/patologia , Neurônios/patologia , Deficiência de Proteína/patologia , Deficiência de Vitamina B 12/patologia , Animais , Peso Corporal , Contagem de Células , Colo/enzimologia , Di-Hidrolipoamida Desidrogenase/metabolismo , Masculino , Plexo Mientérico/enzimologia , NADPH Desidrogenase/metabolismo , Neurônios/enzimologia , Ratos , Ratos Wistar
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