RESUMO
Examination of 54 patients with aseptic necrosis of the femoral head showed that the most characteristic alterations related to this pathology include vegetative-trophic disturbances in zones of autonomic innervation of neurometamers LIII = LIV. Characteristics of the innervation of the femoral head were studied in man and experimental animals.
Assuntos
Necrose da Cabeça do Fêmur/complicações , Articulação do Quadril/inervação , Nervos Periféricos/anatomia & histologia , Doenças do Sistema Nervoso Periférico/etiologia , Adolescente , Adulto , Animais , Gatos , Criança , Diagnóstico Diferencial , Cabeça do Fêmur/inervação , Humanos , Pessoa de Meia-Idade , Dor , Doenças do Sistema Nervoso Periférico/diagnóstico , Radiculopatia/diagnóstico , Ratos , Reflexo Anormal , Doenças da Coluna Vertebral/complicaçõesRESUMO
Molecular cloning has been done of DNA isolated from leukocytes of a patient with T-cell prolymphocytic leukemia. Three HTLV-I-containing recombinant clones have been obtained and their restriction-hybridization analysis performed. None of the clones contained a complete HTLV-I provirus. In all clones, there have been detected nucleotide sequences corresponding to the provirus env-pX-3' LTR region.
Assuntos
Vírus Linfotrópico T Tipo 1 Humano/genética , Leucemia Prolinfocítica/microbiologia , Leucemia de Células T/microbiologia , Clonagem Molecular , Humanos , Hibridização de Ácido NucleicoRESUMO
An association of HTLV-I virus with myelomonocytic leukemia was established by serologic and molecular-biologic procedures. Antibodies to one or two HTLV-I proteins were identified in 10 out of 30 patients with myelomonocytic leukemia; both antibodies to certain HTLV-I proteins and an integrated provirus were detected in 3 cases. Upon examination of donor blood, antibodies to one or two HTLV-I proteins were found in 0.8% cases, but only 0.3% of the examined donors were found positive to HTLV-I. This finding points to the presence of said virus in the population of Latvia.
Assuntos
Infecções por HTLV-I/complicações , Leucemia Mieloide/microbiologia , Idoso , Feminino , Anticorpos Anti-HTLV-I/análise , Infecções por HTLV-I/imunologia , Humanos , Cariotipagem , Leucemia Mieloide/imunologia , Leucemia Mielomonocítica Aguda/microbiologia , Leucemia Mielomonocítica Crônica/microbiologia , Masculino , Pessoa de Meia-IdadeRESUMO
Overall, sixty-seven patients living in different ecological regions were examined to study effects of ecological factors on the catecholamine concentration in biological fluids in patients with chronic posttraumatic osteomyelitis (CPO). The data obtained showed that CPO causes abnormalities of catecholamine metabolism, which get even more aggravated under the influence of an adverse ecological factor, an abnormal radiation impact in particular, this being confirmed by analysis of findings in those patients residing in different ecological regions.