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1.
Bioinformation ; 19(3): 307-309, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37808381

RESUMO

Hypertension occupies a unique position in public health care, because it is the major cause of cardiovascular disease and the most frequent non-communicable disorder seen in primary care globally. The prevalence, treatment, and control rates of hypertension vary greatly by ethnicity. Such disparities are mostly linked to genetic variances, although lifestyle and socioeconomic level may influence health behaviours such as food - both of which appear to be substantial factors. East Asian communities have distinct ethnic traits. Hypertensive individuals are more likely to have salt sensitivity together with modest obesity. East Asians have a greater prevalence of stroke (especially hemorrhagic stroke) and no ischemic heart failure (HF) than Westerners. These problems are typical in both untreated and treated hypertensive patients. White coat hypertension affects 10%-30% of people who visit clinics for high blood pressure, whereas masked hypertension affects 10%-15% of people .With substantial hypertension populations in India and China, clinical studies in these areas are necessary to determine whether existing treatment techniques are effective. All patients with suspected or confirmed hypertension should receive regular lifestyle advice from their doctors, including recommendations for diet and exercise. Expert counsel and more frequent monitoring might be necessary.

2.
Bioinformation ; 19(11): 1051-1056, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38046512

RESUMO

The leading cause of blindness in the world is cataracts, which are dangerous and curable with proper eye care. Eye care service is thought to play significant role in prevention. Nonetheless, not much research has been done to gauge older persons' in rural India's level of cataract awareness and how it relates to their use of eye care services. Therefore, in order to prevent cataracts in the elderly, we described a self-instruction model for cataract knowledge and looked into the variations between pre- and post-test self-instruction models. Their demographic characteristics showed that the higher age group female had highest prevalence of cataracts. The study population's understanding of cataracts is incredibly low: only 2% of participants have adequate knowledge, 52% have somewhat adequate information, and 46% have inadequate knowledge. However, after completing the self-instructional module, 54% of participants felt they knew enough to prevent cataracts. The results of the study showed that the self-instructional module was very helpful in helping the senior population learn about cataract prevention. More interventional research with a larger sample size should be carried out to gain a better understanding of cataract prevention in older adults,.

3.
Bioinformation ; 19(3): 295-298, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37808382

RESUMO

Type-2 Diabetes mellitus is a common metabolic disorder. It is combined with co-morbidities, such as obesity, hyperlipidemia, hypertension and cardiovascular disease which taken together, comprise the 'Metabolic Syndrome'. This disease causes crucial morbidity and mortality at considerable expense to patients, their families and society. Different categories of drugs such as insulin secretagogues, insulin sensitizers, alpha-glucosidase inhibitors, GLP-1 agonists, DPP4 inhibitors, dual PPAR agonists and others are used for its management. Therefore, it is of interest to highlight the recent advances in diagnosis and therapeutics used in the treatment of type-2 diabetes mellitus. The classical and online-literature were used to compile data for this study. This includes the electronic search engine such as Scopus, Google Scholar, Sci Finder, PubMed and Web of Science. Data shows that there are different families of oral and injectable drugs at hand for the treatment of T2DM. Hence, we need to develop a novel, safety and effective agents that will improve the quality of life of T2DM patients, considering effectiveness and durability of lowering blood Glucose, risk of hypoglycemia and diabetes complications.

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