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1.
J Biol Regul Homeost Agents ; 34(5 Suppl. 1): 17-23. IORS Special Issue on Orthopedics, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33739000

RESUMO

Over the past decade, the incidence of revision arthroplasty due to infection has increased substantially, often resulting in multiple surgical interventions with variable success rates and poor clinical outcome. Intraoperative wound irrigation has been proposed to reduce bacterial bioburden and contamination, but currently there is no widely accepted recommendation for the use of topical antiseptics, whether as separate molecules or as a mixed solution. We reviewed studies regarding the use of intraoperative topical antiseptics, their security profile and efficacy in preventing and treating infections of orthopedic implants and introduced a possible combination that may prove valuable in the future.


Assuntos
Anti-Infecciosos Locais , Infecções Relacionadas à Prótese , Ferida Cirúrgica , Humanos , Povidona-Iodo , Infecções Relacionadas à Prótese/tratamento farmacológico , Infecções Relacionadas à Prótese/prevenção & controle , Infecção da Ferida Cirúrgica/prevenção & controle
2.
J Biol Regul Homeost Agents ; 34(3 Suppl. 2): 23-32. ADVANCES IN MUSCULOSKELETAL DISEASES AND INFECTIONS - SOTIMI 2019, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32856436

RESUMO

Over the last years, an increased number of studies have reported the use of cone beam weightbearing computed tomography (WBCT) in the assessment of foot and ankle pathology. This new technology has enabled to overcome the limits inherently related to two-dimensional radiographs (superimposition bias, operator-related bias, rotation bias) and to obtain images reproducing the bones and joints anatomy during physiological standing with a low radiation dose. We performed a review of the current literature to summarize the evidence about the use of 2D or 3D measurements on WBCT images in various foot and ankle conditions. Our aims were to describe measurements proposed so far and to report data on reliability and validity from primary authors.


Assuntos
Tornozelo , Tomografia Computadorizada de Feixe Cônico , Tornozelo/diagnóstico por imagem , Articulação do Tornozelo/diagnóstico por imagem , Imageamento Tridimensional , Reprodutibilidade dos Testes , Suporte de Carga
3.
J Biol Regul Homeost Agents ; 34(3 Suppl. 2): 1-5. ADVANCES IN MUSCULOSKELETAL DISEASES AND INFECTIONS - SOTIMI 2019, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32856433

RESUMO

Two-stage exchange in infected total knee arthroplasty is a reliable technique, but it has a high rate of blood loss. The study aims to compare the pre-operative and post-operative haemoglobin levels, the rate of transfusion, and the blood loss in two-stage exchange. From July 2018 to July 2019, eighteen patients underwent two-stage exchange of their infected total knee arthroplasty. Local and systemic tranexamic acid was administered in both surgical stages. Calculated blood loss was 2246 mL (range 1528 - 2850) in the first stage and 2388 mL (1873 - 2829) during reimplantation, respectively. The corresponding transfusion rate was 55 % and 67%, respectively. With the numbers available, these differences were not significant. In conclusion, this study shows that the blood loss and transfusion rate are similar during the two stages of exchange knee arthroplasty for infection.


Assuntos
Artroplastia do Joelho , Transfusão de Sangue , Antifibrinolíticos , Artroplastia do Joelho/efeitos adversos , Perda Sanguínea Cirúrgica , Humanos , Ácido Tranexâmico
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