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1.
Fertil Steril ; 40(6): 728-33, 1983 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-6653795

RESUMO

Pregnancy outcome in studies of normal reproduction and in programs of in vitro fertilization (IVF) is usually classified as "chemical beta-human chorionic gonadotropin (beta-hCG) abortion," "trimester abortion," and "term delivery." The distinction between a chemical beta-hCG abortion and a first-trimester abortion is not clearly stated in the literature, although such terms are commonly used. It is proposed that in programs of IVF pregnancy outcome be classified as "menstrual abortion," "preclinical abortion," "clinical abortion," or "viable pregnancy." Pregnancy outcome of 190 consecutive cycles induced by human menopausal gonadotropin/human chorionic gonadotropin in the program of IVF at Norfolk is compared with contemporary studies of pregnancy outcome in normal reproduction. The in vitro data indicate that the Norfolk program has recorded no menstrual abortions, a 33% preclinical and clinical abortion rate, and a viable pregnancy rate that approaches but does not equal the term delivery rate of normal reproduction. However, these results have been achieved by the transfer of multiple concepti, whereas normal reproduction depends on the fertilization of a single oocyte.


Assuntos
Aborto Espontâneo/fisiopatologia , Fertilização in vitro , Menstruação , Indução da Ovulação , Testes de Gravidez , Gonadotropina Coriônica/administração & dosagem , Gonadotropina Coriônica/sangue , Feminino , Humanos , Gravidez , Prognóstico
2.
Fertil Steril ; 40(3): 317-21, 1983 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-6411495

RESUMO

One hundred seventy-five cycles in patients with irreparable tubal disease were stimulated by human menopausal gonadotropin/human chorionic gonadotropin for the purpose of in vitro fertilization. As judged by the height of the peripheral estradiol response, the patients were classified as high, intermediate, or low responders. In addition, the estradiol pattern of the response was found to be separable into six categories. The pregnancy rate was found to be related to the height and to the pattern of peripheral response. The overall pregnancy rate in this consecutive series was 19% but varied according to the height and pattern of response from 40% to 0%.


Assuntos
Fertilização in vitro , Fase Folicular , Menstruação , Estradiol/sangue , Feminino , Fase Folicular/efeitos dos fármacos , Humanos , Menotropinas/uso terapêutico , Menstruação/efeitos dos fármacos , Indução da Ovulação , Gravidez
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