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1.
BMC Complement Altern Med ; 18(1): 92, 2018 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-29544493

RESUMO

BACKGROUND: The use of herbal medicine, as one element of complementary and alternative medicine, is increasing worldwide. Little is known about the reasons for and factors associated with its use. This study derives insights for the use of herbal medicine in Germany regarding the usage aims, role played by the type of illness, reasons for preferred usage and sources of information. METHODS: Using a qualitative methodological approach, six focus groups (n = 46) were conducted. Two groups with young, middle-aged and elderly participants, respectively. After audiotaping and verbatim transcription, the data were analysed with a qualitative content analysis. RESULTS: We found that treating illnesses was the most frequently discussed aim for using herbal medicine over all age groups. Preventing illnesses and promoting health were less frequently mentioned overall, but were important for elderly people. Discussions on herbal medicine were associated with either mild/moderate diseases or using herbal medicine as a starting treatment before applying conventional medicine. In this context, participants emphasized the limits of herbal medicine for severe illnesses. Dissatisfaction with conventional treatment, past good experiences, positive aspects associated with herbal medicine, as well as family traditions were the most commonly-mentioned reasons why herbal medicine was preferred as treatment. Concerning information sources, independent reading and family traditions were found to be equally or even more important than consulting medicinal experts. CONCLUSIONS: Although herbal medicine is used mostly for treating mild to moderate illnesses and participants were aware of its limits, the combination of self-medication, non-expert consultation and missing risk awareness of herbal medicine is potentially harmful. This is particularly relevant for elderly users as, even though they appeared to be more aware of health-related issues, they generally use more medicine compared to younger ones. In light of our finding that dissatisfaction with conventional medicine was the most important reason for a preferred use of herbal medicine, government bodies, doctors, and pharmaceutical companies need to be aware of this problem and should aim to establish a certain level of awareness among users concerning this issue.


Assuntos
Fitoterapia/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Terapias Complementares/psicologia , Terapias Complementares/estatística & dados numéricos , Feminino , Grupos Focais , Alemanha , Medicina Herbária , Humanos , Masculino , Pessoa de Meia-Idade , Fitoterapia/psicologia , Adulto Jovem
2.
Rev Gaucha Enferm ; 39(1): e2016-4, 2018.
Artigo em Inglês, Português | MEDLINE | ID: mdl-29846478

RESUMO

OBJECTIVE Our purpose was to discuss practices of cervical cancer prevention among Quilombola Women. METHOD This study used, in 2014, a qualitative research approach aiming twenty women from a quilombola community (people who live in quilombos, descendants of Afro-Brazilian slaves), which is located in Bahia. A semi-structured interview was developed by researchers in order to collect data. The Ethno-nursing Research method was used to analyze the data. RESULTS The use of cultural care through medicinal plants, and the nursing professional care (Pap Smear exam procedure) were stated by Quilombola women as serving as prevention practices against cervical cancer. However, most women stated that they did not use any prevention practices. CONCLUSION Social, cultural and health access issues are practices that are linked to the cervical cancer prevention among Quilombola Women. Therefore, it is indispensable to create an appropriate care plan for Quilombola women's reality.


Assuntos
Anticarcinógenos/uso terapêutico , População Negra , Teste de Papanicolaou , Fitoterapia/métodos , Enfermagem Transcultural/métodos , Neoplasias do Colo do Útero/prevenção & controle , Brasil , Feminino , Humanos , Teoria de Enfermagem , Fitoterapia/psicologia , Pesquisa Qualitativa , Fatores Socioeconômicos , Neoplasias do Colo do Útero/etnologia
3.
Age Ageing ; 46(1): 130-137, 2017 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-28181644

RESUMO

Background: Low diagnostic rates are a barrier to improving care for the growing number of people with dementia in sub-Saharan Africa. Many people with dementia are thought to visit traditional healers (THs) and Christian faith healers (FHs) and these groups may have a role in identifying people with dementia. We aimed to explore the practice and attitudes of these healers regarding dementia in rural Tanzania and investigate attitudes of their patients and their patients' carers. Methods: This was a qualitative study conducted in Hai district, Tanzania. Semi-structured interviews were conducted with a convenience sample of THs and FHs and a purposive-stratified sample of people with dementia and their carers. Interview guides were devised which included case vignettes. Transcripts of interviews were subject to thematic analysis. Findings: Eleven THs, 10 FHs, 18 people with dementia and 17 carers were recruited. Three themes emerged: (i) conceptualisation of dementia by healers as a normal part of the ageing process and no recognition of dementia as a specific condition; (ii) people with dementia and carer reasons for seeking help and experiences of treatment and the role of prayers, plants and witchcraft in diagnosis and treatment; (iii) willingness to collaborate with allopathic healthcare services. FHs and people with dementia expressed concerns about any collaboration with THs. Conclusions: Although THs and FHs do not appear to view dementia as a specific disease, they may provide a means of identifying people with dementia in this setting.


Assuntos
Prestação Integrada de Cuidados de Saúde/métodos , Demência/terapia , Cura pela Fé/psicologia , Conhecimentos, Atitudes e Prática em Saúde , Medicinas Tradicionais Africanas/métodos , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Atitude do Pessoal de Saúde , Cuidadores/psicologia , Cognição , Envelhecimento Cognitivo , Comportamento Cooperativo , Características Culturais , Demência/diagnóstico , Demência/psicologia , Feminino , Humanos , Comunicação Interdisciplinar , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Fitoterapia/psicologia , Extratos Vegetais/uso terapêutico , Plantas Medicinais , Pesquisa Qualitativa , Religião e Medicina , Serviços de Saúde Rural , Tanzânia , Bruxaria/psicologia
4.
BMC Complement Altern Med ; 17(1): 513, 2017 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-29191194

RESUMO

BACKGROUND: Although there are current efforts to integrate herbal medicine (HM) into mainstream healthcare in Ghana, there is paucity of empirical evidence on the acceptability and concurrent use of HM, in the formal health facilities in Ghana. This study sought to determine client perception, disclosure and acceptability of integrating herbal medicine in mainstream healthcare in Kumasi, Ghana. METHODS: A cross-sectional study was conducted from May to August, 2015. Five hundred patients presenting at the outpatient departments of Kumasi South, Suntreso and Tafo Government Hospitals in Kumasi were randomly selected. Interviews were conducted with the use of structured questionnaires. A logistic regression analysis, using backward selection, was conducted to determine the influence of socio-demographic and facility related factors on the odds of using HM at the facility. All statistical tests were two-sided and considered significant at a p-value of <0.05. RESULTS: Majority of the study respondents were females (64.8%) and the median age was 36 years. Less than half, 42.2%, of the respondents utilized HM services when they visited the health facility. Reasons for using HM at the facility level included 'being effective' (24.4%), 'easy to access' (25.3%) and 'being comparatively cheaper' (16%). About 86% never disclosed previous use of HM to their health care providers. Socio-economic status and perception of service provision influenced use of herbal medicines. Respondents who rated themselves wealthy had increased odds of using herbal medicines at the health facility as compared to those who rated themselves poor (OR = 4.9; 95%CI = 1.6-15.3). CONCLUSION: This study shows that integration of herbal medicine is feasible and herbal medicines may be generally accepted as a formal source of healthcare in Ghana. The results of this study might serve as a basis for improvement and upscale of the herbal medicine integration programme in Ghana.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Aceitação pelo Paciente de Cuidados de Saúde , Fitoterapia/psicologia , Fitoterapia/estatística & dados numéricos , Adulto , Estudos Transversais , Feminino , Gana , Medicina Herbária , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Adulto Jovem
5.
Climacteric ; 19(4): 375-80, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27174039

RESUMO

OBJECTIVE: To identify women's sociodemographic and variables related to health care with the prescription of hormonal therapy (HT) and phytotherapy (PT) in Spanish postmenopausal women. METHOD: The survey consisted of a multicenter, observational, cross-sectional, questionnaire-based investigation and was conducted among 3022 postmenopausal women. RESULTS: Of all the women, 31.8% reported the use of systemic HT or PT sometime in their lives. Hot flushes and information received about menopause were the most important variables that influence HT and PT use, although far more intense symptoms were observed in those who were inclined to use HT. The use of HT or PT was more frequently reported among women with high levels of education, who came from private clinics and lived in urban areas. Women who had primary ovarian insufficiency or surgical menopause were inclined to use HT. CONCLUSION: Hot flushes and information received about menopause are the most important variables that influence HT and PT use.


Assuntos
Comportamento de Escolha , Terapia de Reposição de Estrogênios/psicologia , Conhecimentos, Atitudes e Prática em Saúde , Fitoterapia/psicologia , Pós-Menopausa/psicologia , Estudos Transversais , Escolaridade , Feminino , Fogachos/tratamento farmacológico , Humanos , Pessoa de Meia-Idade , Espanha , Inquéritos e Questionários
6.
Neurol Sci ; 37(4): 613-22, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26895323

RESUMO

Though recent progress in multiple sclerosis (MS) treatment is remarkable, numerous unmet needs remain to be addressed often inducing patients to look for complementary and alternative medicines (CAM), especially herbal remedies (HR). HR use, scarcely investigated in MS, may cause adverse reactions (AR) and interfere with conventional treatment. We performed a survey aimed at evaluating use and attitudes towards HR and factor associated to HR use. Other CAM use and attitudes have been investigated as well. Multiple-choice questionnaires were distributed to MS out patients attending 14 Italian referral Centers. Multivariable logistic regression was used to identify HR use determinants. Present/past HR use for either MS or other diseases was reported in 35.6 % of 2419 cases (95 % CI 36.0-40.0 %). CAM use was reported in 42.5 % of cases. Independent predictors of HR use were represented by higher education, geographic area, dissatisfaction with conventional treatment of diseases other than MS and benefit perception from CAM use. Both HR and CAM use were not always disclosed to the healthcare professional. In conclusion, HR and other CAM appear to be popular among MS patients. The involvement of the healthcare professionals appears to be scarce with potential risk of AR or interference with conventional treatments.


Assuntos
Esclerose Múltipla/tratamento farmacológico , Esclerose Múltipla/epidemiologia , Fitoterapia/estatística & dados numéricos , Adolescente , Adulto , Idoso , Criança , Terapias Complementares/psicologia , Terapias Complementares/estatística & dados numéricos , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Itália/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Esclerose Múltipla/psicologia , Análise Multivariada , Fitoterapia/psicologia
7.
Harefuah ; 155(2): 79-82, 133, 2016 Feb.
Artigo em Hebraico | MEDLINE | ID: mdl-27215115

RESUMO

The cannabis plant has been known to humanity for centuries as a remedy for pain, diarrhea and inflammation. Current research is inspecting the use of cannabis for many diseases, including multiple sclerosis, epilepsy, dystonia, and chronic pain. In inflammatory conditions cannabinoids improve pain in rheumatoid arthritis and:pain and diarrhea in Crohn's disease. Despite their therapeutic potential, cannabinoids are not free of side effects including psychosis, anxiety, paranoia, dependence and abuse. Controlled clinical studies investigating the therapeutic potential of cannabis are few and small, whereas pressure for expanding cannabis use is increasing. Currently, as long as cannabis is classified as an illicit drug and until further controlled studies are performed, the use of medical cannabis should be limited to patients who failed conventional better established treatment.


Assuntos
Dor Crônica/tratamento farmacológico , Diarreia/tratamento farmacológico , Controle de Medicamentos e Entorpecentes , Epilepsia/tratamento farmacológico , Maconha Medicinal , Esclerose Múltipla/tratamento farmacológico , Psicoses Induzidas por Substâncias/prevenção & controle , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Cannabis , Dor Crônica/etiologia , Doença de Crohn/complicações , Diarreia/etiologia , Controle de Medicamentos e Entorpecentes/métodos , Controle de Medicamentos e Entorpecentes/organização & administração , Humanos , Prescrição Inadequada/legislação & jurisprudência , Inflamação/tratamento farmacológico , Inflamação/etiologia , Israel , Maconha Medicinal/efeitos adversos , Maconha Medicinal/uso terapêutico , Esclerose Múltipla/complicações , Fitoterapia/métodos , Fitoterapia/psicologia , Fitoterapia/normas , Psicoses Induzidas por Substâncias/etiologia , Transtornos Relacionados ao Uso de Substâncias/etiologia
8.
Anthropol Med ; 23(3): 311-331, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27830941

RESUMO

The paper introduces the Baanashada Dumarka, a Somali fertility therapy carried out by a spirit medium, known locally as 'Alaqad. Baanashada is aimed at women whose fertility issues are believed to be caused by spirits. The study also explores a component of the Baanashada, namely, the use of tiire (Rotheca myricoides), or the butterfly bush. Although Rotheca myricoides is known to possess a number of medicinal components as confirmed by studies of modern science, so far, there exist no studies on its potential (or lack of) fertility effects. Hence, the alleged fertility benefits of the butterfly bush need examining. In 2008 a British Somali woman died of herbs placed in her cervix by a traditional healer in Somaliland. This piece of information indicated not only the role of herbal medicine in fertility practices, but also the popularity of traditional reproductive medicine beyond border, class or educational background. Yet, current research into Somali women's health focuses mainly on Female Genital Mutilation (FGM), examined often without the context of wider cultural practices. This paper, however, suggests that rituals, beliefs and material culture play a paramount role in women's practices. For example, as explored elsewhere, the wagar, a wooden and sacred object made of the African olive, is critical for fertility practices. The current paper illuminates further the significance of reproduction practices in Somali society and the potential continuity of traditions associated with the perpetuation of kinship. It concludes that fertility rituals are part of a wider context of interaction with sacred landscapes, objects and archaeological sites, often associated with past legends in the Horn of Africa.


Assuntos
Clerodendrum , Fármacos para a Fertilidade Feminina/administração & dosagem , Medicinas Tradicionais Africanas/métodos , Fitoterapia/métodos , Plantas Medicinais , Saúde da Mulher/etnologia , Antropologia Médica , Clerodendrum/toxicidade , Cultura , Feminino , Fertilidade , Fármacos para a Fertilidade Feminina/toxicidade , Conhecimentos, Atitudes e Prática em Saúde/etnologia , Humanos , Infertilidade Feminina/etnologia , Infertilidade Feminina/psicologia , Infertilidade Feminina/terapia , Entrevistas como Assunto , Medicinas Tradicionais Africanas/efeitos adversos , Medicinas Tradicionais Africanas/psicologia , Fitoterapia/efeitos adversos , Fitoterapia/psicologia , Plantas Medicinais/toxicidade , Somália
9.
BMC Pregnancy Childbirth ; 15: 208, 2015 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-26341639

RESUMO

BACKGROUND: Sex ratio is an important indicator of development. Despite all the measures undertaken for improvement, it remains an issue of concern in India, with Haryana having a very low sex ratio in the country. Studies have been conducted indicating that consumption of indigenous drugs used for sex selection (SSD) could be strongly associated with adverse effects on the foetal development, including congenital malformations. Some samples of SSDs were collected from parts of North India and analysed in a standard laboratory for its components. METHODS: Thirty SSDs used by the local community were procured from various sources in north India through a rigorous process of collection. These were subjected to laboratory tests to investigate the presence of phytoestrogen and testosterone. Following sample extraction, thin layer chromatography and high performance liquid chromatography were carried out for analysing phytoestrogen content. RESULTS: SSDs were available in various forms such as powder, tablets, mostly from faith healers. Around 87% of the samples collected from sources like doctors, quacks and faith healers were to be taken by the pregnant women after conception; 63% drugs were strongly positive for phytoestrogens (genistein, daidzein, formononetin) and 20% drugs were positive for testosterone. The average dose of the components as calculated after analyses was as follows: daidzein--14.1 mg/g sample, genistein--8.6 mg/g sample, formononetin--5 mg/g sample. CONCLUSION: These SSDs could be potentially detrimental to the growth and development of the foetus. This is likely to have implications on the health of the community. In view of the results obtained in our study, we strongly attest the importance in curbing this harmful practice by banning the supply of the drugs as well as by advocating behavioural changes in the community.


Assuntos
Desenvolvimento Fetal/efeitos dos fármacos , Medicina Tradicional/efeitos adversos , Fitoterapia/efeitos adversos , Pré-Seleção do Sexo/métodos , Feminino , Humanos , Índia , Medicina Tradicional/métodos , Medicina Tradicional/psicologia , Fitoestrógenos/efeitos adversos , Fitoestrógenos/análise , Fitoterapia/métodos , Fitoterapia/psicologia , Gravidez , Pré-Seleção do Sexo/psicologia , Testosterona/efeitos adversos , Testosterona/análise
10.
BMC Complement Altern Med ; 13: 295, 2013 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-24171723

RESUMO

BACKGROUND: Different patient groups are known to use herbal remedies and conventional drugs concomitantly (co-use). This poses a potential risk of herb-drug interaction through altering the drug's pharmacokinetics or pharmacodynamics. Little is known about co-use among patients in general practice. The primary aim of this study was to compare patients in general practice that co-use herbal remedies and conventional drugs with those who do not. The secondary aim was to register the herb-drug combinations with potential clinical relevant interactions among the co-users. METHOD: A questionnaire based cross-sectional study conducted in the autumn 2011 in a general practice office with four general practitioners (GPs) and one intern in Western Norway. Adults >18 years who came for an office visit were invited. The questionnaire asked about demographics, herbal use, conventional drug use and communication about herbal use. Multivariable logistic regression was used to compare co-users to the other patients. RESULTS: Of the 381 patients who completed the questionnaire, the prevalence of herbal use was 44%, with bilberry (41%), green tea (31%), garlic (27%), Aloe vera (26%) and echinacea (18%) as the most frequently used. Among those using conventional drugs regularly, 108 (45%) co-used herbs. Close to 40% of patients on anticoagulants co-used herbs, with garlic and bilberry as the most frequent herbs. Compared to all other patients, co-users had significantly (p < 0.05) increased odds to be female (adjOR 2.0), age above 70 years (adjOR 3.3), use herbs to treat an illness (adjOR 4.2), use two or more herbs (polyherbacy, adjOR 12.1) and having experienced adverse effects of herbal use (adjOR 37.5). Co-use was also associated with use of analgesics or dermatological drugs (adjOR 5.1 and 7.9 respectively). Three out of four patients did not discuss herbal use with any health care professional. CONCLUSION: A sizable proportion of the GP patients co-used herbs with conventional drugs, also combinations with reported interaction potential or additive effects like anticoagulants and garlic. The low disclosure of herbal use to their GP, polyherbacy and the risk of interactions in vulnerable groups like elderly and chronically ill patients, warrant increased awareness among GPs.


Assuntos
Quimioterapia Combinada , Pacientes/psicologia , Fitoterapia , Adulto , Idoso , Idoso de 80 Anos ou mais , Comunicação , Estudos Transversais , Quimioterapia Combinada/psicologia , Feminino , Interações Ervas-Drogas , Medicina Herbária , Humanos , Masculino , Pessoa de Meia-Idade , Noruega , Fitoterapia/psicologia , Extratos Vegetais/uso terapêutico , Inquéritos e Questionários , Adulto Jovem
11.
Harm Reduct J ; 10: 2, 2013 Feb 16.
Artigo em Inglês | MEDLINE | ID: mdl-23414118

RESUMO

BACKGROUND: Despite its increasing prevalence and acceptance among the general public, cannabis use continues to be viewed as an aberrant activity in many contexts. However, little is known about how stigma associated with cannabis use affects individuals who use cannabis for therapeutic purposes (CTP) and what strategies these individuals employ to manage associated stigma. The aim of this Canadian study was to describe users' perceptions of and responses to the stigma attached to using CTP. METHODS: Twenty-three individuals who were using CTP for a range of health problems took part in semi-structured interviews. Transcribed data were analyzed using an inductive approach and comparative strategies to explore participants' perceptions of CTP and identify themes. RESULTS: Participant experiences of stigma were related to negative views of cannabis as a recreational drug, the current criminal sanctions associated with cannabis use, and using cannabis in the context of stigmatizing vulnerability (related to existing illness and disability). Strategies for managing the resulting stigma of using CTP included: keeping CTP 'undercover'; educating those who did not approve of or understand CTP use; and using cannabis responsibly. CONCLUSIONS: Understanding how individuals perceive and respond to stigma can inform the development of strategies aimed at reducing stigma associated with the use of CTP and thereby address barriers faced by those using this medicine.


Assuntos
Cannabis , Doença Crônica/tratamento farmacológico , Fitoterapia/psicologia , Estigma Social , Adaptação Psicológica , Adulto , Idoso , Atitude Frente a Saúde , Colúmbia Britânica , Doença Crônica/psicologia , Feminino , Humanos , Relações Interpessoais , Legislação de Medicamentos , Licenciamento em Medicina/legislação & jurisprudência , Masculino , Pessoa de Meia-Idade , Direitos do Paciente , Percepção , Responsabilidade Social , Estereotipagem
12.
Rev Panam Salud Publica ; 34(2): 121-6, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24096977

RESUMO

OBJECTIVE: To describe knowledge and perceptions regarding the use of oral rehydration solution (ORS) for the management of diarrheal diseases among formal and informal health care providers and community caregivers in the Guatemalan department of Santa Rosa, and to recommend strategies to increase ORS use for management of diarrhea in children. METHODS: From July to September 2008, in-depth, semi-structured interviews were conducted with formal health care providers; open-ended interviews were conducted with informal health care providers; and focus group discussions and pile sorting were carried out with community caregivers. RESULT: The study participants attributed episodes of diarrhea in children to culturally recognized or folk ailments (empacho, cuajo, and varillas) that are primarily treated by traditional healers. There were knowledge deficits about 1) dehydration as a manifestation of diarrhea, and 2) management of dehydration, including the use of ORS and the need to continue feedings during diarrheal episodes. Caregivers perceived bottled/ready-made ORS products and the more expensive over-the-counter antidiarrheal medications as superior to ORS packets in the treatment of diarrhea. CONCLUSIONS: In Guatemala, folk etiologies of disease differ from those of the biomedical establishment and influence the decisions made by caregivers when treating ill children, including those related to the use of ORS. Public health campaigns addressing the treatment and management of diarrheal diseases in Santa Rosa should recognize the ailments known as empacho, cuajo, and varillas and target them for ORS use by community caregivers as well as health care providers in both the formal and informal health sectors.


Assuntos
Atitude do Pessoal de Saúde , Atitude Frente a Saúde , Cuidadores/psicologia , Desidratação/terapia , Diarreia/terapia , Hidratação/psicologia , Pessoal de Saúde/psicologia , Soluções para Reidratação/uso terapêutico , Adolescente , Adulto , Antidiarreicos/uso terapêutico , Pré-Escolar , Cultura , Desidratação/tratamento farmacológico , Desidratação/etiologia , Desidratação/mortalidade , Diarreia/complicações , Diarreia/mortalidade , Diarreia Infantil/complicações , Diarreia Infantil/mortalidade , Diarreia Infantil/terapia , Escolaridade , Feminino , Grupos Focais , Guatemala/epidemiologia , Promoção da Saúde , Humanos , Lactente , Masculino , Medicina Tradicional/psicologia , Pessoa de Meia-Idade , Medicamentos sem Prescrição , Fitoterapia/psicologia , Fitoterapia/estatística & dados numéricos , Pesquisa Qualitativa , Estudos de Amostragem , Terminologia como Assunto , Adulto Jovem
13.
Holist Nurs Pract ; 27(1): 6-12, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23211383

RESUMO

Relationships between primary care patients' herbal use and influencing factors were examined. Most felt that herbals were safer than prescription medications and preferred their use. There were significant relationships between perceived herbal safety and efficacy and other motivational factors with use. Supplement cost and demographics were less predictive of use.


Assuntos
Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Fitoterapia/métodos , Fitoterapia/psicologia , Preparações de Plantas/uso terapêutico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Pessoa de Meia-Idade
14.
Pharmacology ; 89(1-2): 83-90, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22343362

RESUMO

BACKGROUND: Curcumin is the active principle of Curcuma longa, one of the widely used components in the traditional system of medicine in India. Despite its efficacy in experimental studies aiming at neuronal disorders like depression, curcu-min's poor water solubility challenges the production of therapeutic formulations. This study investigates the antidepressant-like activity of novel water-soluble curcumin formulations, dispensed in three different concentrations. Further, the study comparatively evaluates St. John's wort (SJW), another herbal preparation. METHODS: These compounds were evaluated in the forced swimming test in mice, and the corresponding changes in the neurotransmitter levels were measured. RESULTS: Three water-soluble curcumin formulations, C-5, C-20 and C-50 (50-200 mg/kg p.o.) decreased the immobility period, and increased serotonin and dopamine levels in the brain tissues. A subeffective dose (50 mg/kg) of these formulations enhanced the antidepressant-like effect of classical antidepressants with varied mechanisms of action. In addition, an SJW dose of 25 mg/kg showed a significant antidepressant-like effect in all the behavioral studies and also significantly increased brain neurotransmitter levels, especially that of serotonin. The effects produced by C-5 were comparable with those of SJW and fluoxetine, respectively. CONCLUSION: In all these observations, the water-soluble formulations showed a significant antidepressant-like effect, including enhancement of neurotransmitter levels as compared to the similar dose of a conventional curcumin preparation. Thus, these formulations may be used as a novel treatment option in the management of mental depression.


Assuntos
Antidepressivos/uso terapêutico , Química Farmacêutica/métodos , Curcumina/uso terapêutico , Depressão/tratamento farmacológico , Hypericum/química , Fitoterapia/psicologia , Extratos Vegetais/uso terapêutico , Animais , Antidepressivos/química , Antidepressivos/farmacologia , Aminas Biogênicas/metabolismo , Encéfalo/efeitos dos fármacos , Encéfalo/metabolismo , Curcumina/química , Curcumina/farmacologia , Depressão/metabolismo , Modelos Animais de Doenças , Relação Dose-Resposta a Droga , Avaliação Pré-Clínica de Medicamentos/métodos , Avaliação Pré-Clínica de Medicamentos/psicologia , Quimioterapia Combinada/psicologia , Resposta de Imobilidade Tônica/efeitos dos fármacos , Masculino , Camundongos , Camundongos Endogâmicos , Atividade Motora/efeitos dos fármacos , Fitoterapia/métodos , Extratos Vegetais/farmacologia , Solubilidade , Fatores de Tempo
15.
Asian Pac J Cancer Prev ; 23(1): 319-325, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-35092401

RESUMO

OBJECTIVE: Cancer treatments often cause side effects. Cannabis is a plant that has been studied and used to treat and relieve side effects from modern medicine. Medical cannabis (MC) was legalized in Thailand in 2019 with limited research on demand for its use. Therefore, this study aimed to identify factors associated with demand for MC use among cancer patients in the North of Thailand. METHODS: This analytical cross-sectional study administered a multistage random sampling to recruit 1,284 cancer patients in northern Thailand to response a self-administered structured questionnaire. Generalized Linear Mixed Model (GLMM) was used to identify the determinants of demand for MC use among the population, presented adjusted odds ratios (adj.OR), 95% confidence intervals (95% CI), and p-values. RESULT: Nearly half of the respondents reported demand to use MC (44.0%). The factors that were significantly associated with demand to use MC included had high levels of health literacy about MC (adj.OR = 5.70; 95% CI: 4.08 to 7.96), higher levels of social support (adj.OR =5.50; 95% CI: 3.60 to 8.39), positive attitudes toward MC use (adj.OR = 2.56; 95% CI: 1.83 to 3.56), aged less than 30 (adj.OR =1.89; 95% CI: 1.21 to 2.93), diagnosis with cancerfor more than 12 months ago (adj.OR =1.73; 95% CI: 1.19 to 2.52) when controlling effect of other covariates. CONCLUSION: We found substantial demand for MC use among cancer patients. Health literacy,social support, attitudes about MC, age, and duration of having cancer were significantly associated with demand for MC use. Therefore, improving health literacy and social support, especially among older cancer patients, could help increasing demand for MC as a complementary medicine to treat cancers.


Assuntos
Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Maconha Medicinal/uso terapêutico , Neoplasias/tratamento farmacológico , Neoplasias/psicologia , Fitoterapia/psicologia , Adulto , Fatores Etários , Estudos Transversais , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Letramento em Saúde , Humanos , Masculino , Razão de Chances , Apoio Social , Tailândia , Fatores de Tempo
16.
J Psychiatry Neurosci ; 36(6): 375-82, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21463543

RESUMO

BACKGROUND: Monoamine oxidase A (MAO-A) inhibitor antidepressants raise levels of multiple monoamines, whereas the selective serotonin reuptake inhibitors (SSRIs) only raise extracellular serotonin. Despite this advantage of MAO-A inhibitors, there is much less frequent development of MAO inhibitors compared with SSRIs. We sought to measure brain MAO-A occupancy after 6 weeks of treatment in depressed patients with a clinically effective dose of a selective MAO-A inhibitor and measure MAO-A occupancy after repeated administration of St. John's wort, an herb purported to have MAO-A inhibitor properties. METHODS: Participants underwent 2 [(11)C]-harmine positron emission tomography scans. Healthy controls completed a test-retest condition, and depressed patients were scanned before and after repeated administration of moclobemide or St. John's wort for 6 weeks at the assigned dose. We measured MAO-A VT, an index of MAO-A density, in the prefrontal, anterior cingulate and anterior temporal cortices, putamen, thalamus, midbrain and hippocampus. RESULTS: We included 23 participants (10 controls and 13 patients with major depressive disorder [MDD]) in our study. Monoamine oxidase A VT decreased significantly throughout all regions after moclobemide treatment in patients with MDD compared with controls (repeated-measures analysis of variance, F1,15 = 71.08-130.06, p < 0.001 for all regions, mean occupancy 74% [standard deviation 6%]). Treatment with St. John's wort did not significantly alter MAO-A VT. LIMITATIONS: The occupancy estimates are limited by the sample size of each treatment group; hence, our estimate for the overall moclobemide occupancy of 74% has a 95% confidence interval of 70%-78%, and we can estimate with 95% certainty that the occupancy of St. John's wort is less than 5%. CONCLUSION: For new MAO-A inhibitors, about 74% occupancy at steady-state dosing is desirable. Consistent with this, St. John's wort should not be classified as an MAO-A inhibitor. The magnitude of MAO-A blockade during moclobemide treatment exceeds the elevation of MAO-A binding during illness by at least 30%, suggesting that the treatment effect should exceed the disease effect when designing selective antidepressants for this target.


Assuntos
Encéfalo/enzimologia , Transtorno Depressivo Maior/enzimologia , Harmina , Moclobemida/farmacologia , Inibidores da Monoaminoxidase/farmacologia , Monoaminoxidase/metabolismo , Preparações de Plantas/farmacologia , Adulto , Encéfalo/diagnóstico por imagem , Encéfalo/efeitos dos fármacos , Radioisótopos de Carbono , Transtorno Depressivo Maior/diagnóstico por imagem , Transtorno Depressivo Maior/tratamento farmacológico , Feminino , Humanos , Hypericum , Masculino , Pessoa de Meia-Idade , Moclobemida/uso terapêutico , Inibidores da Monoaminoxidase/uso terapêutico , Fitoterapia/psicologia , Preparações de Plantas/uso terapêutico , Tomografia por Emissão de Pósitrons/métodos , Tomografia por Emissão de Pósitrons/psicologia , Ensaio Radioligante/métodos
17.
J Clin Pharm Ther ; 36(3): 367-75, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21545616

RESUMO

WHAT IS KNOWN AND OBJECTIVE: Biologically based therapies (BBTs) such as herbal medicines represent the most commonly used type of complementary and alternative medicine by cancer patients. There is a paucity of data regarding individuals' motives for starting and continuing use of BBTs in cancer. Our objective is to explore lay perspectives on use of BBTs in cancer. Our hope is that the data generated will support pharmacists and other professionals in improving their communication about BBTs with patients. METHODS: Interviews with 12 individuals with cancer who used BBTs were analyzed with interpretive description and framework analysis, to build on previous literature and gain new knowledge of clinical relevance. RESULTS: The findings suggest that users are motivated to continue to use BBTs when they experience these as both effective and harmless. Perceived effects of BBTs include a wide range of responses such as improved physical and psychological well-being, and cancer-related benefits. These experiences go beyond the legal health and medical claims for these products. The findings indicate that users' views of side-effects, ascribed to BBT use, are situation-dependent with the potential to either facilitate or hinder continued BBT use. WHAT IS NEW AND CONCLUSION: Our results indicate the importance of acknowledging users' own views of BBTs to improve patient-provider communication. This should aid the design of more effective BBT surveillance systems and hence increase patient safety and satisfaction.


Assuntos
Antineoplásicos/uso terapêutico , Atitude Frente a Saúde , Produtos Biológicos/uso terapêutico , Terapias Complementares/psicologia , Neoplasias/psicologia , Neoplasias/terapia , Adulto , Idoso , Antineoplásicos/efeitos adversos , Antineoplásicos Fitogênicos/efeitos adversos , Antineoplásicos Fitogênicos/uso terapêutico , Produtos Biológicos/efeitos adversos , Terapias Complementares/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Motivação , Neoplasias/tratamento farmacológico , Fitoterapia/efeitos adversos , Fitoterapia/psicologia , Autocuidado/psicologia , Automedicação/psicologia , Suécia , Análise e Desempenho de Tarefas , Resultado do Tratamento
18.
BMC Complement Altern Med ; 11: 117, 2011 Nov 25.
Artigo em Inglês | MEDLINE | ID: mdl-22117933

RESUMO

BACKGROUND: Over three-quarter of the world's population is using herbal medicines with an increasing trend globally. Herbal medicines may be beneficial but are not completely harmless.This study aimed to assess the extent of use and the general knowledge of the benefits and safety of herbal medicines among urban residents in Lagos, Nigeria. METHODS: The study involved 388 participants recruited by cluster and random sampling techniques. Participants were interviewed with a structured open- and close-ended questionnaire.The information obtained comprises the demography and types of herbal medicines used by the respondents; indications for their use; the sources, benefits and adverse effects of the herbal medicines they used. RESULTS: A total of 12 herbal medicines (crude or refined) were used by the respondents, either alone or in combination with other herbal medicines. Herbal medicines were reportedly used by 259 (66.8%) respondents. 'Agbo jedi-jedi' (35%) was the most frequently used herbal medicine preparation, followed by 'agbo-iba' (27.5%) and Oroki herbal mixture® (9%). Family and friends had a marked influence on 78.4% of the respondents who used herbal medicine preparations. Herbal medicines were considered safe by half of the respondents despite 20.8% of those who experienced mild to moderate adverse effects. CONCLUSIONS: Herbal medicine is popular among the respondents but they appear to be ignorant of its potential toxicities. It may be necessary to evaluate the safety, efficacy and quality of herbal medicines and their products through randomised clinical trial studies. Public enlightenment programme about safe use of herbal medicines may be necessary as a means of minimizing the potential adverse effects.


Assuntos
Medicina Herbária , Fitoterapia/estatística & dados numéricos , Saúde da População Urbana , Adulto , Feminino , Humanos , Conhecimento , Masculino , Pessoa de Meia-Idade , Nigéria , Fitoterapia/psicologia , Inquéritos e Questionários , Adulto Jovem
19.
Subst Use Misuse ; 46(6): 769-80, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21138343

RESUMO

The purpose of this qualitative study was to describe how individuals who self-report therapeutic use of cannabis perceive its health effects. Data from 23 individual interviews were transcribed and analyzed. Understandings of gendered roles and identities were used to explore the data and interpret differences in perceptions. Descriptions of the health benefits of cannabis for therapeutic purposes included cannabis as life preserving, a disease therapy, a medicine for the mind, a means for self-management, and a way to manage addiction. Self-management of risks focused on the potential effects of excessive use, smoking-related risks, and purchasing precautions. Although the reports of women and men were similar in many respects, there were important differences in patterns and practices of use that reflected gender influences. Insights from the study provide direction for developing gender-specific information to support decision making and usage for therapeutic users.


Assuntos
Atitude Frente a Saúde , Cannabis , Usuários de Drogas/psicologia , Fitoterapia/psicologia , Automedicação/psicologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Caracteres Sexuais
20.
Nurs Clin North Am ; 56(1): 69-78, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33549287

RESUMO

The use of alternative therapies for health problems specific to women is increasing. As many as 67% of women admit to using complementary therapies of some kind, including supplements, chiropractic intervention, acupuncture, and acupressure. Many women turn to herbal supplements because they think that pharmacologic interventions are unsafe or not effective. Current literature provides conflicting information regarding many complementary and alternative therapies, including herbal supplements. Although most are not harmful, it is important to review the safety and efficacy of supplements for women's health issues.


Assuntos
Atitude Frente a Saúde , Suplementos Nutricionais/estatística & dados numéricos , Fitoterapia/estatística & dados numéricos , Saúde da Mulher , Medicina Baseada em Evidências , Feminino , Humanos , Medicina Integrativa/estatística & dados numéricos , Terapias Mente-Corpo , Fitoterapia/psicologia
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