[Effect of hormone replacement with tibolone on plasma insulin and blood glucose in postmenopause]. / Efecto del reemplazo hormonal con tibolona sobre la insulina plasmática y la glucemia en la posmenopausia.
Ginecol Obstet Mex
; 69: 301-3, 2001 Aug.
Article
en Es
| MEDLINE
| ID: mdl-11599314
ABSTRACT
The effect of Tibolone, and estrogen-like therapeutic agent used for menopause, on insulin and glucose was investigated in 18 healthy postmenopausal women. At baseline and after 3 months of Tibolone, 2.5 mg daily, blood levels of glucose and insulin were evaluated in each participant. Fasting levels of glucose were not modified by Tibolone, whereas plasmatic insulin levels were reduced significantly (p < 0.01). High-density lipoprotein cholesterol and total cholesterol were not affected by Tibolone. From these data it may be suggested that Tibolone does not negatively influence glucose fasting levels, but reduces the already elevated insulin levels which may be due to an improvement in peripheral tissue sensitivity to insulin.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Glucemia
/
Posmenopausia
/
Terapia de Reemplazo de Hormonas
/
Moduladores de los Receptores de Estrógeno
/
Insulina
/
Norpregnenos
Límite:
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
Es
Revista:
Ginecol Obstet Mex
Año:
2001
Tipo del documento:
Article