Bone modeling controlled by a nickel-titanium shape memory alloy intramedullary nail.
Biomaterials
; 23(12): 2535-43, 2002 Jun.
Article
en En
| MEDLINE
| ID: mdl-12033601
ABSTRACT
Nitinol (NiTi) shape memory metal alloy makes it possible to prepare functional implants that apply a continuous bending force to the bone. The purpose of this study was to find out if bone modeling can be controlled with a functional intramedullary NiTi nail. Pre-shaped intramedullary NiTi nails (length 26 mm, thickness 1.0-1.4 mm) with a curvature radius of 25-37 mm were implanted in the cooled martensite form in the medullary cavity of the right femur in eight rats, where they restored their austenite form, causing a bending force. After 12 weeks, the operated femurs were compared with their non-operated contralateral counterpairs. Anteroposterior radiographs demonstrated significant bowing, as indicated by the angle between the distal articular surface and the long axis of the femur (p = 0.003). Significant retardation of longitudinal growth and thickening of operated femurs were also seen. Quantitative densitometry showed a significant increase in the average cross-sectional cortical area (p = 0.001) and cortical thickness (p = 0.002), which were most obvious in the mid-diaphyseal area. Cortical bone mineral density increased in the proximal part of the bone and decreased in the distal part. Polarized light microscopy of the histological samples revealed that the new bone induced by the functional intramedullary nail was mainly woven bone. In conclusion, this study showed that bone modeling can be controlled with a functional intramedullary nail made of nickel-titanium shape memory alloy.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Clavos Ortopédicos
/
Aleaciones
/
Fémur
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Biomaterials
Año:
2002
Tipo del documento:
Article
País de afiliación:
Finlandia