Burkholderia cepacia complex infection in a cohort of Italian patients with cystic fibrosis.
J Microbiol
; 45(3): 275-9, 2007 Jun.
Article
en En
| MEDLINE
| ID: mdl-17618236
ABSTRACT
The aims of this study were to detect Burkholderia cepacia complex (Bcc) strains in a cohort of Cystic Fibrosis patients (n=276) and to characterize Bcc isolates by molecular techniques. The results showed that 11.23% of patients were infected by Bcc. Burkholderia cenocepacia lineage III-A was the most prevalent species (64.3%) and, of these, 10% was cblA positive and 50% esmR positive. Less than half of the strains were sensitive to ceftazidime, meropenem, piperacillin tazobactam, and trimethoprim-sulfamethoxazole. About half of the strains (41%) had homogeneous profiles, suggesting cross-transmission. The infection by B. cenocepacia was associated to a high rate of mortality (p=0.01).
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por Burkholderia
/
Fibrosis Quística
/
Complejo Burkholderia cepacia
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Microbiol
Asunto de la revista:
MICROBIOLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Italia