Association of HELLP syndrome with primary antiphospholipid syndrome--a case report.
Clin Rheumatol
; 27(1): 111-3, 2008 Jan.
Article
en En
| MEDLINE
| ID: mdl-17684701
ABSTRACT
Authors present the first Hungarian case of a young pregnant woman with the association of antiphospholipid syndrome (APS) and hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. After the onset of severe preeclampsia, the pregnancy was terminated but the patient's condition continued to worsen. New symptoms of APS, including deep vein thrombosis and ischemic nervus opticus lesion, developed in the patient followed by the onset of acute respiratory distress syndrome, which required respiratory therapy. Intensive treatment with plasmapheresis, high-dose intravenous immunoglobulin, high-dose corticosteroids, cyclophosphamide, and anticoagulants eventually led to full recovery. There have been only few scattered reports in the literature on the association of HELLP syndrome and APS, which was successfully managed with the combination of various immunosuppressive and immunomodulatory treatment modalities.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Síndrome Antifosfolípido
/
Síndrome HELLP
/
Anticuerpos Antifosfolípidos
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Clin Rheumatol
Año:
2008
Tipo del documento:
Article
País de afiliación:
Hungria