trans-Acting factors and cis elements involved in glucose repression of arabinan degradation in Bacillus subtilis.
J Bacteriol
; 189(22): 8371-6, 2007 Nov.
Article
en En
| MEDLINE
| ID: mdl-17827291
ABSTRACT
In Bacillus subtilis, the synthesis of enzymes involved in the degradation of arabinose-containing polysaccharides is subject to carbon catabolite repression (CCR). Here we show that CcpA is the major regulator of repression of the arabinases genes in the presence of glucose. CcpA acts via binding to one cre each in the promoter regions of the abnA and xsa genes and to two cres in the araABDLMNPQ-abfA operon. The contributions of the coeffectors HPr and Crh to CCR differ according to growth phase. HPr dependency occurs during both exponential growth and the transitional phase, while Crh dependency is detected mainly at the transitional phase. Our results suggest that Crh synthesis may increase at the end of exponential growth and consequently contribute to this effect, together with other factors.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polisacáridos
/
Bacillus subtilis
/
Transactivadores
/
Glucosa
Idioma:
En
Revista:
J Bacteriol
Año:
2007
Tipo del documento:
Article
País de afiliación:
Portugal