[Laryngectomy as a salvage procedure of the patients with massive postradiation injury of the larynx]. / Laryngektomia jako postepowanie ratujace u chorych z nasilonym odczynem popromiennym po radioterapii raka krtani.

ABSTRACT

INTRODUCTION: Author discusses problems and treatment principles of patients with massive postradiation injury, who had laryngectomy procedure as a result of insufficience of the farmacological treatment. MATERIAL AND METHODS: There were 12 patients who were performed laryngectomy as a treatment of massive postradiation injury of the larynx in the period 1975-2005. We suspected presence of persistent neoplasm with postradiation changes. Seven laryngectomies were performed after confirmation of the neoplasm in 1-3 biopsies. Three patients were treated operatively without this confirmation in spite of two biopsies which were negatively, and two patients were treated in this way without biopsies. RESULTS: Two patients had tomour free postlaryngectomy specimens in the histopathological examinations, and among 10 others the reccurence of the tumour after radiotherapy was present during the post-laryngectomy histopathological examinations. In 7 cases this reccurence was proved with massive postradiation injury in endoscopic biopsies before laryngectomy. DISCUSSION: Author presents his own problems and presents methods of treatment of the patients with massive postradiation injury of the larynx described in literature.