Impact of live donor age (>or=50) on liver transplantation.
Transplant Proc
; 39(10): 3189-93, 2007 Dec.
Article
en En
| MEDLINE
| ID: mdl-18089350
ABSTRACT
BACKGROUND:
The question of whether donor age negatively impacts recipient outcome in adult-to-adult living donor liver transplantation (LDLT) is rarely discussed. The aim of this study was to evaluate the impact of older donor age (50 years or older) on recipient outcomes in adult-to-adult LDLT.METHODS:
LDLT data were retrospectively evaluated from our 299 LDLT cases in 297 recipients, which were divided into 2 groups a younger group (group Y, donor age<50, n=237) and an older group (Group O, donor age>or=50, n=62). Clinical parameters of both recipients and donors were comparable between groups.RESULTS:
There was no difference between the groups in patient survival or postoperative complications of either donors or recipients. In recipients, graft regeneration was significantly impaired in Group O. Graft function, including protein synthesis and cholestasis, was comparable between the 2 groups.CONCLUSION:
Although the regeneration capacity of aged grafts was impaired, the function of grafts from older donors was comparable to that of those from younger donors. There was no difference in the clinical outcomes between the groups.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Factores de Edad
/
Trasplante de Hígado
/
Donadores Vivos
Tipo de estudio:
Observational_studies
Límite:
Adult
/
Aged
/
Humans
/
Middle aged
Idioma:
En
Revista:
Transplant Proc
Año:
2007
Tipo del documento:
Article
País de afiliación:
Japón