Multiple pilomatricomas and gliomatosis cerebri--a new association?
Pediatr Dermatol
; 26(1): 75-8, 2009.
Article
en En
| MEDLINE
| ID: mdl-19250412
ABSTRACT
Pilomatricomas are benign skin tumors originating from hair follicle matrix cells. In 2% to 3.5% of cases they occur in multiplicity and then may be associated with genetic diseases, such as myotonic dystrophy Curschmann-Steinert, familial adenomatous polyposis (Gardner syndrome), and Rubinstein-Taybi syndrome. A 15-year-old boy treated with temozolomide and oxcarbazepine for gliomatosis cerebri with symptomatic epilepsy developed four firm cutaneous nodules on his face and right upper arm in the course of 1 year. All four tumors were excised under local anesthesia. Histological examination confirmed the clinical diagnosis of pilomatricomas. This is the first published case of a patient suffering from gliomatosis cerebri and developing multiple pilomatricomas. Whether this observation represents a new association or is a mere coincidence cannot be clarified at present.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Neoplasias Encefálicas
/
Pilomatrixoma
/
Neoplasias Neuroepiteliales
/
Enfermedades del Cabello
Tipo de estudio:
Risk_factors_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Pediatr Dermatol
Año:
2009
Tipo del documento:
Article
País de afiliación:
Alemania