Actions of estrogens on glial cells: Implications for neuroprotection.
Biochim Biophys Acta
; 1800(10): 1106-12, 2010 Oct.
Article
en En
| MEDLINE
| ID: mdl-19818384
ABSTRACT
Glial cells are directly or indirectly affected by estradiol and by different estrogenic compounds, such as selective estrogen receptor modulators. Acting on oligodendrocytes, astrocytes and microglia, estrogens regulate remyelination, edema formation, extracellular glutamate levels and the inflammatory response after brain injury. In addition, estradiol induces the expression and release of growth factors by glial cells that promote neuronal survival. Therefore, glial cells are important players in the neuroprotective and reparative mechanisms of estrogenic compounds.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Oligodendroglía
/
Astrocitos
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Microglía
/
Fármacos Neuroprotectores
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Estrógenos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
2010
Tipo del documento:
Article
País de afiliación:
España