Multicenter study of prevalence of nontuberculous mycobacteria in patients with cystic fibrosis in france.
J Clin Microbiol
; 47(12): 4124-8, 2009 Dec.
Article
en En
| MEDLINE
| ID: mdl-19846643
ABSTRACT
We performed a multicenter prevalence study of nontuberculous mycobacteria (NTM) involving 1,582 patients (mean age, 18.9 years; male/female ratio, 1.06) with cystic fibrosis in France. The overall NTM prevalence (percentage of patients with at least one positive culture) was 6.6% (104/1,582 patients), with prevalences ranging from 3.7% (in the east of France) to 9.6% (in the greater Paris area). Mycobacterium abscessus complex (MABSC; 50 patients) and Mycobacterium avium complex (MAC; 23 patients) species were the most common NTM, and the only ones associated with fulfillment of the American Thoracic Society bacteriological criteria for NTM lung disease. The "new" species, Mycobacterium bolletii and Mycobacterium massiliense, accounted for 40% of MABSC isolates. MABSC species were isolated at all ages, with a prevalence peak between 11 and 15 years of age (5.8%), while MAC species reached their highest prevalence value among patients over 25 years of age (2.2%).
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Complejo Mycobacterium avium
/
Infección por Mycobacterium avium-intracellulare
/
Fibrosis Quística
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Micobacterias no Tuberculosas
/
Infecciones por Mycobacterium no Tuberculosas
Tipo de estudio:
Clinical_trials
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
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Adult
/
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Clin Microbiol
Año:
2009
Tipo del documento:
Article
País de afiliación:
Francia