Synthesis and Fluorescent Properties of Biodegradable Hyperbranched Poly(amido amine)s.
Macromol Rapid Commun
; 30(24): 2096-101, 2009 Dec 16.
Article
en En
| MEDLINE
| ID: mdl-21638500
ABSTRACT
Disulfide-functionalized hyperbranched poly(amido amine)s (HPAMAMs) were synthesized by Michael addition polymerization of N,N'-cystaminebisacrylamide and 1-(2-aminoethyl)piperazine. The novel HPAMAMs displayed bright fluorescence, and the emissions bands cover nearly the whole visible wavelength range. When polymer solutions were excited at 330-385, 460-490, and 510-550 nm, blue, green, and red solutions were observed, respectively. The HPAMAMs are biodegradable and they can be easily cleaved by 2-mercaptoethanol or glutathione, leading to a decrease in the fluorescence intensity. Studies of applications of the biocompatible and biodegradable HPAMAMs in fluorescence imaging technology and biological science are in progress.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Macromol Rapid Commun
Año:
2009
Tipo del documento:
Article