Neurotransmitter corelease: mechanism and physiological role.
Annu Rev Physiol
; 74: 225-43, 2012.
Article
en En
| MEDLINE
| ID: mdl-22054239
ABSTRACT
Neurotransmitter identity is a defining feature of all neurons because it constrains the type of information they convey, but many neurons release multiple transmitters. Although the physiological role for corelease has remained poorly understood, the vesicular uptake of one transmitter can regulate filling with the other by influencing expression of the H(+) electrochemical driving force. In addition, the sorting of vesicular neurotransmitter transporters and other synaptic vesicle proteins into different vesicle pools suggests the potential for distinct modes of release. Corelease thus serves multiple roles in synaptic transmission.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Transmisión Sináptica
/
Neurotransmisores
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Annu Rev Physiol
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos