[Nondetectable prostate cancer in radical prostatectomy specimens]. / Kimutathatatlan prosztatarák radikális prostatectomiás szövetmintákban.
Orv Hetil
; 153(3): 113-7, 2012 Jan 22.
Article
en Hu
| MEDLINE
| ID: mdl-22236417
ABSTRACT
UNLABELLED Since the widespread use of prostate-specific antigen, early diagnosis of prostate cancer at an early stage has been increased. Consequently, a greater frequency of low-volume disease or no tumor has been found in radical prostatectomy specimen. AIMS:
In the present study authors analyzed patients classified as pT0 after radical prostatectomy at their center.METHODS:
1134 radical prostatectomies were evaluated retrospectively at the author's center between 1996 and 2010. If there was no evidence of prostate cancer in the specimen, patient was staged as pT0. Patients were divided into two groups received neoadjuvant hormonal therapy or not.RESULTS:
Overall 32 (2.8%) patients were staged as pT0. The rate of pT0 staging was 9.3% and 1.2% in the hormonally treated group and non-hormonally treated group. False-positive prostate biopsy was found in 2 cases. The rate of pT0 staging was higher in patients with incidental prostate cancer, low Gleason score and enlarged prostate. Biochemical relapse was observed in 3 pT0 patients in the hormonally treated group, among them there was one clinical relapse. In non-hormonally treated group no recurrence was detected.CONCLUSION:
The rate of pT0 staging was higher in the hormonally treated group. Because of biochemical and clinical relapse despite vanishing prostate cancer phenomenon, these cases are considered not to be true pT0. On the basis of present study and other reports the rate of pT0 staging is about one percentage in non-hormonally treated patients. Prognosis of these patients is excellent.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Prostatectomía
/
Neoplasias de la Próstata
/
Biomarcadores de Tumor
/
Antígeno Prostático Específico
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Screening_studies
Límite:
Aged
/
Aged80
/
Humans
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Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
Hu
Revista:
Orv Hetil
Año:
2012
Tipo del documento:
Article