RPF: a quality assessment tool for protein NMR structures.
Nucleic Acids Res
; 40(Web Server issue): W542-6, 2012 Jul.
Article
en En
| MEDLINE
| ID: mdl-22570414
ABSTRACT
We describe the RPF web server, a quality assessment tool for protein NMR structures. The RPF server measures the 'goodness-of-fit' of the 3D structure with NMR chemical shift and unassigned NOESY data, and calculates a discrimination power (DP) score, which estimates the differences between the fits of the query structures and random coil structures to these experimental data. The DP-score is an accuracy predictor of the query structure. The RPF server also maps local structure quality measures onto the 3D structure using an online molecular viewer, and onto the NMR spectra, allowing refinement of the structure and/or NOESY peak list data. The RPF server is available at http//nmr.cabm.rutgers.edu/rpf.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Conformación Proteica
/
Programas Informáticos
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Resonancia Magnética Nuclear Biomolecular
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Nucleic Acids Res
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos