Dynamic modeling of cellular populations within iBioSim.
ACS Synth Biol
; 2(5): 223-9, 2013 May 17.
Article
en En
| MEDLINE
| ID: mdl-23654252
ABSTRACT
As the complexity of synthetic genetic circuits increases, modeling is becoming a necessary first step to inform subsequent experimental efforts. In recent years, the design automation community has developed a wealth of computational tools for assisting experimentalists in designing and analyzing new genetic circuits at several scales. However, existing software primarily caters to either the DNA- or single-cell level, with little support for the multicellular level. To address this need, the iBioSim software package has been enhanced to provide support for modeling, simulating, and visualizing dynamic cellular populations in a two-dimensional space. This capacity is fully integrated into the software, capitalizing on iBioSim's strengths in modeling, simulating, and analyzing single-celled systems.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Simulación por Computador
/
Lenguajes de Programación
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Interfaz Usuario-Computador
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Programas Informáticos
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Fenómenos Fisiológicos Celulares
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Biología Sintética
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Modelos Biológicos
Límite:
Animals
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Humans
Idioma:
En
Revista:
ACS Synth Biol
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos