OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.

Fiil, Berthe Katrine; Damgaard, Rune Busk; Wagner, Sebastian Alexander; Keusekotten, Kirstin; Fritsch, Melanie; Bekker-Jensen, Simon; Mailand, Niels; Choudhary, Chunaram; Komander, David; Gyrd-Hansen, Mads

Fiil, Berthe Katrine; Damgaard, Rune Busk; Wagner, Sebastian Alexander; Keusekotten, Kirstin; Fritsch, Melanie; Bekker-Jensen, Simon; Mailand, Niels; Choudhary, Chunaram; Komander, David; Gyrd-Hansen, Mads.

Afiliación

Fiil BK; Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Damgaard RB; Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Wagner SA; Department of Proteomics Novo, Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Keusekotten K; Medical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Fritsch M; Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Bekker-Jensen S; Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Mailand N; Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Choudhary C; Department of Proteomics Novo, Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Komander D; Medical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Gyrd-Hansen M; Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.

Mol Cell ; 50(6): 818-830, 2013 Jun 27.

Article en En | MEDLINE | ID: mdl-23806334

Asunto(s)

Endopeptidasas/fisiología; Inmunidad Innata; Metionina/metabolismo; Transducción de Señal; Ubiquitinación; Expresión Génica; Técnicas de Silenciamiento del Gen; Células HEK293; Humanos; Mediadores de Inflamación/metabolismo; FN-kappa B/metabolismo; Proteína Adaptadora de Señalización NOD2/metabolismo; Mapeo de Interacción de Proteínas; Proteína Serina-Treonina Quinasa 2 de Interacción con Receptor/metabolismo; Proteína Inhibidora de la Apoptosis Ligada a X/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Transducción de Señal / Ubiquitinación / Inmunidad Innata / Metionina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2013 Tipo del documento: Article País de afiliación: Dinamarca

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