[Long term outcome of atrial fibrillation patients with KCNA5 and NPPA mutations post circumferential pulmonary vein ablation].
Zhonghua Xin Xue Guan Bing Za Zhi
; 41(5): 387-9, 2013 May.
Article
en Zh
| MEDLINE
| ID: mdl-24021120
ABSTRACT
OBJECTIVE:
The outcome of atrial fibrillation patients with genetic mutations post ablation was not well evaluated. METHODS ANDRESULTS:
Three atrial fibrillation patients with evidence of mutations in KCNA5 and NPPA post successful circumferential pulmonary vein ablation were included. Mutation in KCNA5 was found in one male patient with paroxysmal atrial fibrillation. He was free of atrial fibrillation post ablation after 46 months follow-up. Mutations in NPPA were found in two male patients with persistent atrial fibrillation and they were free from atrial fibrillation after 64 months and 38 months follow-up post circumferential pulmonary vein ablation, roof line and mitral isthmus line ablation.CONCLUSION:
Satisfactory long term results are observed in atrial fibrillation patients with KCNA5 and NPPA mutations post circumferential pulmonary vein ablation.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fibrilación Atrial
/
Factor Natriurético Atrial
/
Ablación por Catéter
/
Canal de Potasio Kv1.5
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Xin Xue Guan Bing Za Zhi
Año:
2013
Tipo del documento:
Article
País de afiliación:
China