Claudin-2 is an independent negative prognostic factor in breast cancer and specifically predicts early liver recurrences.

Kimbung, Siker; Kovács, Anikó; Bendahl, Pär-Ola; Malmström, Per; Fernö, Mårten; Hatschek, Thomas; Hedenfalk, Ingrid

Kimbung, Siker; Kovács, Anikó; Bendahl, Pär-Ola; Malmström, Per; Fernö, Mårten; Hatschek, Thomas; Hedenfalk, Ingrid.

Afiliación

Kimbung S; Division of Oncology, Department of Clinical Sciences, Lund, Lund University, Sweden; CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden.
Kovács A; Department of Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Bendahl PO; Division of Oncology, Department of Clinical Sciences, Lund, Lund University, Sweden.
Malmström P; Division of Oncology, Department of Clinical Sciences, Lund, Lund University, Sweden; Skåne Department of Oncology, Skåne University Hospital, Lund, Sweden.
Fernö M; Division of Oncology, Department of Clinical Sciences, Lund, Lund University, Sweden.
Hatschek T; Department of Oncology and Pathology, Karolinska Institutet and Karolinska University Hospital, Sweden.
Hedenfalk I; Division of Oncology, Department of Clinical Sciences, Lund, Lund University, Sweden; CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden. Electronic address: Ingrid.Hedenfalk@med.lu.se.

Mol Oncol ; 8(1): 119-28, 2014 Feb.

Article en En | MEDLINE | ID: mdl-24287398

Asunto(s)

Neoplasias de la Mama/patología; Mama/patología; Claudina-2/análisis; Neoplasias Hepáticas/secundario; Recurrencia Local de Neoplasia/secundario; Regulación hacia Arriba; Mama/metabolismo; Neoplasias de la Mama/diagnóstico; Neoplasias de la Mama/genética; Claudina-2/genética; Estudios de Cohortes; Femenino; Humanos; Hígado/metabolismo; Hígado/patología; Neoplasias Hepáticas/diagnóstico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patología; Persona de Mediana Edad; Recurrencia Local de Neoplasia/diagnóstico; Recurrencia Local de Neoplasia/genética; Recurrencia Local de Neoplasia/patología; Pronóstico; Transcriptoma

Palabras clave

BCSS; Breast cancer; CI; CLDN2; Claudin-2; ER; HR; IHC; LNM; LiMFS; Liver metastasis; OR; PR; Prognostic biomarker; RFS; TMA; breast cancer specific survival; claudin-2 mRNA; confidence interval; estrogen receptor; hazard ratio; immunohistochemistry; liver metastasis-free survival; lymph node metastasis; odds ratio; progesterone receptor; relapse-free survival; tissue microarray

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mama / Neoplasias de la Mama / Regulación hacia Arriba / Claudina-2 / Neoplasias Hepáticas / Recurrencia Local de Neoplasia Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Suecia

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