Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5.

Ashino, Takashi; Ohkubo-Morita, Haruyo; Yamamoto, Masayuki; Yoshida, Takemi; Numazawa, Satoshi

Ashino, Takashi; Ohkubo-Morita, Haruyo; Yamamoto, Masayuki; Yoshida, Takemi; Numazawa, Satoshi.

Afiliación

Ashino T; Division of Toxicology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Ohkubo-Morita H; Division of Toxicology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Yamamoto M; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Yoshida T; Division of Toxicology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Numazawa S; Division of Toxicology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.

Redox Biol ; 2: 284-8, 2014.

Article en En | MEDLINE | ID: mdl-24494203

Asunto(s)

Hidrocarburo de Aril Hidroxilasas/genética; Cetonas/administración & dosificación; Hígado/metabolismo; Factor 2 Relacionado con NF-E2/metabolismo; Fenobarbital/administración & dosificación; Esteroide Hidroxilasas/genética; Animales; Familia 2 del Citocromo P450; Regulación de la Expresión Génica/efectos de los fármacos; Hemo-Oxigenasa 1/genética; Cetonas/farmacología; Masculino; Proteínas de la Membrana/genética; Ratones; Ratones Endogámicos C57BL; NAD(P)H Deshidrogenasa (Quinona)/genética; Factor 2 Relacionado con NF-E2/genética; Fenobarbital/farmacología; Transducción de Señal/efectos de los fármacos

Palabras clave

ARE, antioxidant response element; CAR, constitutive androstane receptor; Cyp2a5; Cyp2b10; Gapdh, glyceraldehyde-3-phosphate dehydrogenase; Hmox1, heme oxygenase-1; Maf, musculoaponeurotic fibrosarcoma oncogene homolog; Mouse; Nqo1, NAD(P)H-quinone oxidoreductase-1; Nrf2, nuclear-factor erythroid 2-related factor 2; Nuclear-factor erythroid 2-related factor 2; P450, cytochrome P450; PBREM, phenobarbital responsive element module; PCR, polymerase chain reaction; Phenobarbital; Phorone

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenobarbital / Esteroide Hidroxilasas / Hidrocarburo de Aril Hidroxilasas / Factor 2 Relacionado con NF-E2 / Cetonas / Hígado Límite: Animals Idioma: En Revista: Redox Biol Año: 2014 Tipo del documento: Article País de afiliación: Japón

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