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Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.
Xu, Xianzhong; Pulavarti, Surya V S R K; Eletsky, Alexander; Huang, Yuanpeng Janet; Acton, Thomas B; Xiao, Rong; Everett, John K; Montelione, Gaetano T; Szyperski, Thomas.
Afiliación
  • Xu X; Department of Chemistry, The State University of New York at Buffalo and Northeast Structural Genomics Consortium, Buffalo, NY, 14260, USA.
J Struct Funct Genomics ; 15(4): 201-7, 2014 Dec.
Article en En | MEDLINE | ID: mdl-24941917
ABSTRACT
High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas de Unión al Calcio / Proteínas de Homeodominio / Proteínas de Unión al ADN / Proteínas Reguladoras de la Apoptosis / Proteínas de Neoplasias / Neoplasias Límite: Humans Idioma: En Revista: J Struct Funct Genomics Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas de Unión al Calcio / Proteínas de Homeodominio / Proteínas de Unión al ADN / Proteínas Reguladoras de la Apoptosis / Proteínas de Neoplasias / Neoplasias Límite: Humans Idioma: En Revista: J Struct Funct Genomics Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos