DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human.

Simar, David; Versteyhe, Soetkin; Donkin, Ida; Liu, Jia; Hesson, Luke; Nylander, Vibe; Fossum, Anna; Barrès, Romain

Simar, David; Versteyhe, Soetkin; Donkin, Ida; Liu, Jia; Hesson, Luke; Nylander, Vibe; Fossum, Anna; Barrès, Romain.

Afiliación

Simar D; Inflammation and Infection Research, School of Medical Sciences, UNSW Australia, Sydney NSW 2052, Australia. Electronic address: d.simar@unsw.edu.au.
Versteyhe S; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Donkin I; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Liu J; Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia, Sydney NSW 2052, Australia.
Hesson L; Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia, Sydney NSW 2052, Australia.
Nylander V; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Fossum A; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
Barrès R; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; School of Medical Sciences, UNSW Australia, Sydney NSW 2052, Australia. Electronic address: barres@sund.ku.dk.

Metabolism ; 63(9): 1188-97, 2014 Sep.

Article en En | MEDLINE | ID: mdl-24996265

Asunto(s)

Linfocitos B/metabolismo; Metilación de ADN; Diabetes Mellitus Tipo 2/metabolismo; Células Asesinas Naturales/metabolismo; Obesidad/metabolismo; Regulación hacia Arriba; Adolescente; Adulto; Linfocitos B/patología; Índice de Masa Corporal; Células Cultivadas; Estudios de Cohortes; Diabetes Mellitus Tipo 2/sangre; Diabetes Mellitus Tipo 2/inmunología; Epigénesis Genética; Humanos; Resistencia a la Insulina; Células Asesinas Naturales/patología; Leucocitos Mononucleares/metabolismo; Leucocitos Mononucleares/patología; Masculino; Persona de Mediana Edad; Monocitos/metabolismo; Monocitos/patología; Obesidad/inmunología; Linfocitos T/metabolismo; Linfocitos T/patología; Adulto Joven

Palabras clave

Epigenetic changes; Flow cytometry; Leukocytes; Metabolic diseases

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos B / Células Asesinas Naturales / Regulación hacia Arriba / Metilación de ADN / Diabetes Mellitus Tipo 2 / Obesidad Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Revista: Metabolism Año: 2014 Tipo del documento: Article

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