Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation.

Zhu, Yun-Rong; Xu, Yong; Fang, Jian-Feng; Zhou, Feng; Deng, Xiong-Wei; Zhang, Yun-Qing

Zhu, Yun-Rong; Xu, Yong; Fang, Jian-Feng; Zhou, Feng; Deng, Xiong-Wei; Zhang, Yun-Qing.

Afiliación

Zhu YR; Department of Orthopedics, The Affiliated Jiangyin Hospital of Medical College of Southeast University, Jiangyin City, Jiangsu 214400, China.
Xu Y; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Fang JF; Department of Orthopedics, The Affiliated Jiangyin Hospital of Medical College of Southeast University, Jiangyin City, Jiangsu 214400, China.
Zhou F; Department of Orthopedics, The Affiliated Jiangyin Hospital of Medical College of Southeast University, Jiangyin City, Jiangsu 214400, China.
Deng XW; Department of Orthopedics, The Affiliated Jiangyin Hospital of Medical College of Southeast University, Jiangyin City, Jiangsu 214400, China.
Zhang YQ; Department of Orthopedics, The Affiliated Jiangyin Hospital of Medical College of Southeast University, Jiangyin City, Jiangsu 214400, China. Electronic address: yunqingzhang@126.com.

Biochem Biophys Res Commun ; 451(1): 112-8, 2014 Aug 15.

Article en En | MEDLINE | ID: mdl-25068992

Asunto(s)

Apoptosis/efectos de los fármacos; Neoplasias Óseas/tratamiento farmacológico; Bufanólidos/farmacología; Estrés del Retículo Endoplásmico/efectos de los fármacos; Osteoblastoma/tratamiento farmacológico; Animales; Neoplasias Óseas/metabolismo; Neoplasias Óseas/patología; Caspasa 12/metabolismo; Cinamatos/farmacología; Relación Dosis-Respuesta a Droga; Silenciador del Gen; Humanos; Masculino; Ratones; Ratones SCID; Osteoblastoma/metabolismo; Osteoblastoma/patología; Tiourea/análogos & derivados; Tiourea/farmacología; Factor de Transcripción CHOP/genética; Factor de Transcripción CHOP/metabolismo; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Apoptosis and signaling; Bufotalin; ER stress; Osteoblastoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Óseas / Bufanólidos / Apoptosis / Osteoblastoma / Estrés del Retículo Endoplásmico Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochem Biophys Res Commun Año: 2014 Tipo del documento: Article País de afiliación: China

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