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Identification of one-electron reductases that activate both the hypoxia prodrug SN30000 and diagnostic probe EF5.
Wang, Jingli; Guise, Chris P; Dachs, Gabi U; Phung, Yen; Hsu, Annie Huai-Ling; Lambie, Neil K; Patterson, Adam V; Wilson, William R.
Afiliación
  • Wang J; Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland, New Zealand.
  • Guise CP; Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand.
  • Dachs GU; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Pathology, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand.
  • Phung Y; Department of Pathology, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand.
  • Hsu AH; Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland, New Zealand.
  • Lambie NK; Department of Anatomical Pathology, Prince of Wales Hospital, Barker Street, Randwick, NSW 2031, Australia.
  • Patterson AV; Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand.
  • Wilson WR; Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand. Electronic address: wr.wilson@auckland.ac.nz.
Biochem Pharmacol ; 91(4): 436-46, 2014 Oct 15.
Article en En | MEDLINE | ID: mdl-25130546

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Triazinas / Profármacos / Hipoxia de la Célula / Óxidos N-Cíclicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Biochem Pharmacol Año: 2014 Tipo del documento: Article País de afiliación: Nueva Zelanda

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Triazinas / Profármacos / Hipoxia de la Célula / Óxidos N-Cíclicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Biochem Pharmacol Año: 2014 Tipo del documento: Article País de afiliación: Nueva Zelanda