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Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.
Chakraborty, Rikhia; Hampton, Oliver A; Shen, Xiaoyun; Simko, Stephen J; Shih, Albert; Abhyankar, Harshal; Lim, Karen Phaik Har; Covington, Kyle R; Trevino, Lisa; Dewal, Ninad; Muzny, Donna M; Doddapaneni, Harshavardhan; Hu, Jianhong; Wang, Linghua; Lupo, Philip J; Hicks, M John; Bonilla, Diana L; Dwyer, Karen C; Berres, Marie-Luise; Poulikakos, Poulikos I; Merad, Miriam; McClain, Kenneth L; Wheeler, David A; Allen, Carl E; Parsons, D Williams.
Afiliación
  • Chakraborty R; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX;
  • Hampton OA; Department of Molecular and Human Genetics, Human Genome Sequencing Center.
  • Shen X; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX;
  • Simko SJ; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Division of Pediatric Hematology-Oncology, Department of Pediatrics.
  • Shih A; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX;
  • Abhyankar H; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX;
  • Lim KP; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Program in Translational Biology and Molecular Medicine, and.
  • Covington KR; Department of Molecular and Human Genetics, Human Genome Sequencing Center.
  • Trevino L; Department of Molecular and Human Genetics, Human Genome Sequencing Center.
  • Dewal N; Department of Molecular and Human Genetics, Human Genome Sequencing Center.
  • Muzny DM; Human Genome Sequencing Center.
  • Doddapaneni H; Human Genome Sequencing Center.
  • Hu J; Human Genome Sequencing Center.
  • Wang L; Department of Molecular and Human Genetics, Human Genome Sequencing Center.
  • Lupo PJ; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Division of Pediatric Hematology-Oncology, Department of Pediatrics.
  • Hicks MJ; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Division of Pediatric Hematology-Oncology, Department of Pediatrics, Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX;
  • Bonilla DL; Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX; and.
  • Dwyer KC; Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX; and.
  • Berres ML; Department of Oncological Sciences, Tisch Cancer Institute, Immunology Institute, and.
  • Poulikakos PI; Department of Oncological Sciences, Tisch Cancer Institute, Department of Dermatology, Icahn School of Medicine, New York, NY.
  • Merad M; Department of Oncological Sciences, Tisch Cancer Institute, Immunology Institute, and.
  • McClain KL; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Division of Pediatric Hematology-Oncology, Department of Pediatrics.
  • Wheeler DA; Department of Molecular and Human Genetics, Human Genome Sequencing Center.
  • Allen CE; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Division of Pediatric Hematology-Oncology, Department of Pediatrics, Program in Translational Biology and Molecular Medicine, and.
  • Parsons DW; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX; Department of Molecular and Human Genetics, Human Genome Sequencing Center, Division of Pediatric Hematology-Oncology, Department of Pediatrics, Program in Translational Biology and Molecular Medicine, and.
Blood ; 124(19): 3007-15, 2014 Nov 06.
Article en En | MEDLINE | ID: mdl-25202140
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Histiocitosis de Células de Langerhans / Proteínas Proto-Oncogénicas B-raf / MAP Quinasa Quinasa 1 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Histiocitosis de Células de Langerhans / Proteínas Proto-Oncogénicas B-raf / MAP Quinasa Quinasa 1 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article