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Simultaneous targeting of PI3Kδ and a PI3Kδ-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia.
Wang, Xiang; Zhang, Xi; Li, Ben-shang; Zhai, Xiaowen; Yang, Zhuo; Ding, Li-xia; Wang, Hongsheng; Liang, Chris; Zhu, Weiliang; Ding, Jian; Meng, Ling-hua.
Afiliación
  • Wang X; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhang X; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Li BS; Department of Hematology and Oncology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Zhai X; Department of Hematology and Oncology, Children's Hospital of Fudan University, Shanghai, China.
  • Yang Z; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Ding LX; Department of Hematology and Oncology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Wang H; Department of Hematology and Oncology, Children's Hospital of Fudan University, Shanghai, China.
  • Liang C; Xcovery, LLC, West Palm Beach, Florida, USA.
  • Zhu W; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Ding J; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Meng LH; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Oncotarget ; 5(21): 10732-44, 2014 Nov 15.
Article en En | MEDLINE | ID: mdl-25313141
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Purinas / Bencimidazoles / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas Serina-Treonina Quinasas / Sistema de Señalización de MAP Quinasas / MAP Quinasa Quinasa 1 / MAP Quinasa Quinasa 2 / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-akt / Inhibidores de las Quinasa Fosfoinosítidos-3 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Oncotarget Año: 2014 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Purinas / Bencimidazoles / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas Serina-Treonina Quinasas / Sistema de Señalización de MAP Quinasas / MAP Quinasa Quinasa 1 / MAP Quinasa Quinasa 2 / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-akt / Inhibidores de las Quinasa Fosfoinosítidos-3 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Oncotarget Año: 2014 Tipo del documento: Article País de afiliación: China