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Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line.
Essletzbichler, Patrick; Konopka, Tomasz; Santoro, Federica; Chen, Doris; Gapp, Bianca V; Kralovics, Robert; Brummelkamp, Thijn R; Nijman, Sebastian M B; Bürckstümmer, Tilmann.
Afiliación
  • Essletzbichler P; Haplogen GmbH, 1030 Vienna, Austria;
  • Konopka T; Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), 1090 Vienna, Austria;
  • Santoro F; Haplogen GmbH, 1030 Vienna, Austria;
  • Chen D; Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), 1090 Vienna, Austria;
  • Gapp BV; Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), 1090 Vienna, Austria;
  • Kralovics R; Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), 1090 Vienna, Austria;
  • Brummelkamp TR; Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), 1090 Vienna, Austria; The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Nijman SM; Haplogen GmbH, 1030 Vienna, Austria; Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), 1090 Vienna, Austria;
  • Bürckstümmer T; Haplogen GmbH, 1030 Vienna, Austria;
Genome Res ; 24(12): 2059-65, 2014 Dec.
Article en En | MEDLINE | ID: mdl-25373145
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Eliminación de Secuencia / Sistemas CRISPR-Cas / Haploidia Límite: Humans Idioma: En Revista: Genome Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2014 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Eliminación de Secuencia / Sistemas CRISPR-Cas / Haploidia Límite: Humans Idioma: En Revista: Genome Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2014 Tipo del documento: Article