The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering.

Ellis, Stephanie J; Lostchuck, Emily; Goult, Benjamin T; Bouaouina, Mohamed; Fairchild, Michael J; López-Ceballos, Pablo; Calderwood, David A; Tanentzapf, Guy

Ellis, Stephanie J; Lostchuck, Emily; Goult, Benjamin T; Bouaouina, Mohamed; Fairchild, Michael J; López-Ceballos, Pablo; Calderwood, David A; Tanentzapf, Guy.

Afiliación

Ellis SJ; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Lostchuck E; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Goult BT; School of Biosciences, University of Kent, Canterbury, Kent, United Kingdom.
Bouaouina M; Department of Pharmacology, Yale University, New Haven, Connecticut, United States of America; Carnegie Mellon University Qatar, Education City, Doha, Qatar.
Fairchild MJ; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
López-Ceballos P; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Calderwood DA; Department of Pharmacology, Yale University, New Haven, Connecticut, United States of America.
Tanentzapf G; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.

PLoS Genet ; 10(11): e1004756, 2014 Nov.

Article en En | MEDLINE | ID: mdl-25393120

Asunto(s)

Adhesión Celular/genética; Desarrollo Embrionario/genética; Integrinas/genética; Talina/genética; Alelos; Animales; Membrana Celular/genética; Membrana Celular/metabolismo; Drosophila melanogaster/embriología; Embrión no Mamífero; Matriz Extracelular/genética; Matriz Extracelular/metabolismo; Recuperación de Fluorescencia tras Fotoblanqueo; Integrinas/metabolismo; Mutación Puntual; Estructura Terciaria de Proteína; Talina/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Integrinas / Adhesión Celular / Talina / Desarrollo Embrionario Límite: Animals Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Canadá

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