The neuroprotective actions of oestradiol and oestrogen receptors.
Nat Rev Neurosci
; 16(1): 17-29, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25423896
ABSTRACT
Hormones regulate homeostasis by communicating through the bloodstream to the body's organs, including the brain. As homeostatic regulators of brain function, some hormones exert neuroprotective actions. This is the case for the ovarian hormone 17ß-oestradiol, which signals through oestrogen receptors (ERs) that are widely distributed in the male and female brain. Recent discoveries have shown that oestradiol is not only a reproductive hormone but also a brain-derived neuroprotective factor in males and females and that ERs coordinate multiple signalling mechanisms that protect the brain from neurodegenerative diseases, affective disorders and cognitive decline.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Receptores de Estrógenos
/
Estradiol
/
Neuroprostanos
Límite:
Animals
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Female
/
Humans
/
Male
Idioma:
En
Revista:
Nat Rev Neurosci
Asunto de la revista:
NEUROLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
España