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A natural genetic variant of granzyme B confers lethality to a common viral infection.
Andoniou, Christopher E; Sutton, Vivien R; Wikstrom, Matthew E; Fleming, Peter; Thia, Kevin Y T; Matthews, Antony Y; Kaiserman, Dion; Schuster, Iona S; Coudert, Jerome D; Eldi, Preethi; Chaudhri, Geeta; Karupiah, Gunasegaran; Bird, Phillip I; Trapani, Joseph A; Degli-Esposti, Mariapia A.
Afiliación
  • Andoniou CE; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.
  • Sutton VR; Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Wikstrom ME; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.
  • Fleming P; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.
  • Thia KY; Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Matthews AY; Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia.
  • Kaiserman D; Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia.
  • Schuster IS; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.
  • Coudert JD; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.
  • Eldi P; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia.
  • Chaudhri G; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia.
  • Karupiah G; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia.
  • Bird PI; Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia.
  • Trapani JA; Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.
  • Degli-Esposti MA; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.
PLoS Pathog ; 10(12): e1004526, 2014 Dec.
Article en En | MEDLINE | ID: mdl-25502180
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Virosis / Muromegalovirus / Infecciones por Herpesviridae / Granzimas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2014 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Virosis / Muromegalovirus / Infecciones por Herpesviridae / Granzimas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2014 Tipo del documento: Article País de afiliación: Australia