Mefloquine, an anti-malaria agent, causes reactive oxygen species-dependent cell death in mast cells via a secretory granule-mediated pathway.

Paivandy, Aida; Calounova, Gabriela; Zarnegar, Behdad; Ohrvik, Helena; Melo, Fabio R; Pejler, Gunnar

Paivandy, Aida; Calounova, Gabriela; Zarnegar, Behdad; Ohrvik, Helena; Melo, Fabio R; Pejler, Gunnar.

Afiliación

Paivandy A; Departement of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences Uppsala, Sweden.
Calounova G; Departement of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences Uppsala, Sweden.
Zarnegar B; Department of Medical Biochemistry and Microbiology, Uppsala University Uppsala, Sweden.
Ohrvik H; Departement of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences Uppsala, Sweden.
Melo FR; Departement of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences Uppsala, Sweden.
Pejler G; Departement of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences Uppsala, Sweden.

Pharmacol Res Perspect ; 2(6): e00066, 2014 Dec.

Article en En | MEDLINE | ID: mdl-25505612

Palabras clave

Apoptosis; granules; mast cells; mefloquine, mMCP-6; reactive oxygen species; serglycin; tryptase

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Pharmacol Res Perspect Año: 2014 Tipo del documento: Article País de afiliación: Suecia

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