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Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists.
Ryu, HyungChul; Seo, Sejin; Lee, Jee-Young; Ha, Tae-Hwan; Lee, Sunho; Jung, Aeran; Ann, Jihyae; Kim, Sung-Eun; Yoon, Suyoung; Hong, Mannkyu; Blumberg, Peter M; Frank-Foltyn, Robert; Bahrenberg, Gregor; Schiene, Klaus; Stockhausen, Hannelore; Christoph, Thomas; Frormann, Sven; Lee, Jeewoo.
Afiliación
  • Ryu H; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Seo S; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Lee JY; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Ha TH; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Lee S; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Jung A; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Ann J; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Kim SE; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Yoon S; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Hong M; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Blumberg PM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Frank-Foltyn R; Grunenthal Innovation, Grunenthal GmbH, D-52078 Aachen, Germany.
  • Bahrenberg G; Grunenthal Innovation, Grunenthal GmbH, D-52078 Aachen, Germany.
  • Schiene K; Grunenthal Innovation, Grunenthal GmbH, D-52078 Aachen, Germany.
  • Stockhausen H; Grunenthal Innovation, Grunenthal GmbH, D-52078 Aachen, Germany.
  • Christoph T; Grunenthal Innovation, Grunenthal GmbH, D-52078 Aachen, Germany.
  • Frormann S; Grunenthal Innovation, Grunenthal GmbH, D-52078 Aachen, Germany.
  • Lee J; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address: jeewoo@snu.ac.kr.
Eur J Med Chem ; 93: 101-8, 2015 Mar 26.
Article en En | MEDLINE | ID: mdl-25659771
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridinas / Sulfonamidas / Bencenoacetamidas / Canales Catiónicos TRPV / Analgésicos Límite: Animals Idioma: En Revista: Eur J Med Chem Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridinas / Sulfonamidas / Bencenoacetamidas / Canales Catiónicos TRPV / Analgésicos Límite: Animals Idioma: En Revista: Eur J Med Chem Año: 2015 Tipo del documento: Article