SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.

Hasegawa, Kazuteru; Sin, Ho-Su; Maezawa, So; Broering, Tyler J; Kartashov, Andrey V; Alavattam, Kris G; Ichijima, Yosuke; Zhang, Fan; Bacon, W Clark; Greis, Kenneth D; Andreassen, Paul R; Barski, Artem; Namekawa, Satoshi H

Hasegawa, Kazuteru; Sin, Ho-Su; Maezawa, So; Broering, Tyler J; Kartashov, Andrey V; Alavattam, Kris G; Ichijima, Yosuke; Zhang, Fan; Bacon, W Clark; Greis, Kenneth D; Andreassen, Paul R; Barski, Artem; Namekawa, Satoshi H.

Afiliación

Hasegawa K; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Sin HS; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Maezawa S; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Broering TJ; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Kartashov AV; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Alavattam KG; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Ichijima Y; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Zhang F; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Bacon WC; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Greis KD; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Andreassen PR; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Barski A; Division of Allergy and Immunology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA.
Namekawa SH; Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 49267, USA. Electronic address: satoshi.namekawa

Dev Cell ; 32(5): 574-88, 2015 Mar 09.

Article en En | MEDLINE | ID: mdl-25703348

Asunto(s)

Epigenómica; Regulación del Desarrollo de la Expresión Génica; Histonas/metabolismo; Complejo Represivo Polycomb 1/metabolismo; Testículo/metabolismo; Ubiquitina/metabolismo; Proteínas Adaptadoras Transductoras de Señales; Animales; Biomarcadores/metabolismo; Western Blotting; Proteínas de Ciclo Celular; Células Cultivadas; Inmunoprecipitación de Cromatina; Proteínas Cromosómicas no Histona; Femenino; Perfilación de la Expresión Génica; Silenciador del Gen; Células Germinativas; Técnicas para Inmunoenzimas; Péptidos y Proteínas de Señalización Intracelular/fisiología; Masculino; Meiosis/genética; Ratones; Ratones Noqueados; Análisis de Secuencia por Matrices de Oligonucleótidos; Complejo Represivo Polycomb 1/genética; Complejo Represivo Polycomb 1/fisiología; ARN Mensajero/genética; Reacción en Cadena en Tiempo Real de la Polimerasa; Proteínas Represoras/fisiología; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Cromosomas Sexuales/genética; Espermatogénesis; Testículo/citología; Ubiquitina-Proteína Ligasas/fisiología; Ubiquitinación

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Testículo / Histonas / Regulación del Desarrollo de la Expresión Génica / Ubiquitina / Epigenómica / Complejo Represivo Polycomb 1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Dev Cell Asunto de la revista: EMBRIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google